Microbiology: A Systems Approach
5th Edition
ISBN: 9781259706615
Author: Marjorie Kelly Cowan Professor
Publisher: McGraw-Hill Education
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Chapter 17, Problem 2CTQ
Summary Introduction
To determine: Whether a highly specific or highly sensitive diagnostic test should be preferred in the middle of a measles outbreak.
Concept introduction:
“Specificity and sensitivity” are two statistical measures to determine the efficiency of a binary classification test. This test is used to identify whether an individual has a disease or not.
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Allata brought her 6 month old baby Anna to the clinic for immunization. She told the nurse that Jena has already received BCG and a first dose of DT when she was 8 weeks old. Mrs. Alita was not able to bring Anna to the clinic for her next DPT immunization because they went to the province. She is asking the nurse if Anna can still receive her DPT immunization. The nurse's reply is that:
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Scenario: In a rural community, a primary health care nurse is conducting a door-to-door vaccination campaign to address a recent outbreak of measles. The nurse notices that many parents are hesitant to vaccinate their children due to misinformation. The nurse decides to organize an educational seminar to address these concerns. What approach should the nurse take to effectively communicate the importance of vaccination?
Options:
A) Use complex medical terms to explain the effectiveness of vaccines.
B) Distribute printed materials without engaging in direct conversation.
C) Employ a culturally sensitive communication strategy, using simple language and visual aids.
D) Recommend vaccination without providing any rationale.
You are presented with the following clinical scenario:
"A 12 month old male child presents with recurrent bacterial infections. Flow cytometry shows a complete lack of B-
lymphocytes."
Using your knowledge of immunology and flow cytometry, identify which dot plots represent the healthy control and
patient samples in each scenario and come up with a clinical diagnosis. Note that you may need to use additional
background sources to fully understand what is going on at the cellular level for each diagnosis.
What is the clinical diagnosis
O HIV/AIDS O COVID-19 O LAD type 1
U
E
CD4-FITC
CD8-PE
CD45-PE
CD8-PE
70%
13%
52%
10%
82%
5%
27%
5%
CD8-PE
CD4-FITC
CD20-FITC
CD4-FITC
17%
38%
13%
68%
Agammaglobulinaemia
CD45-PE
CD4-FITC
CD45-PE
CD45-PE
35%
3%
62%
8%
93%
22%
CD15-FITC
CD8-PE
CD20-FITC
CD15-FITC
Select the flow cytometry dot plot that corresponds to the healthy control sample
Select the flow cytometry dot plot that corresponds to the patient sample
62%
30%
0%
77%
Chapter 17 Solutions
Microbiology: A Systems Approach
Ch. 17.1 - Prob. 1AYPCh. 17.1 - Prob. 2AYPCh. 17.1 - Prob. 3AYPCh. 17.1 - Prob. 4AYPCh. 17.2 - Summarize the most common methods used for direct...Ch. 17.2 - Prob. 6AYPCh. 17.2 - Prob. 7AYPCh. 17.3 - Prob. 8AYPCh. 17.3 - Differentiate between sensitivity and specificity.Ch. 17.3 - Explain how fluorescent antibodies can be used in...
Ch. 17.3 - Prob. 11AYPCh. 17.3 - Prob. 12AYPCh. 17.3 - Prob. 13AYPCh. 17.3 - Explain the difference between a direct and an...Ch. 17.4 - Prob. 15AYPCh. 17.4 - Prob. 16AYPCh. 17.4 - Prob. 17AYPCh. 17.5 - Prob. 18AYPCh. 17.5 - List the major advantages of microarray methods of...Ch. 17.5 - Summarize the benefits of using whole-genome...Ch. 17 - Prob. 1MCQCh. 17 - Prob. 2MCQCh. 17 - Prob. 3MCQCh. 17 - Prob. 4MCQCh. 17 - Prob. 5MCQCh. 17 - Prob. 6MCQCh. 17 - Prob. 7MCQCh. 17 - Prob. 8MCQCh. 17 - The Western blot test can be used to identify a....Ch. 17 - Prob. 10MCQCh. 17 - True-False Questions. If the statement is true,...Ch. 17 - Prob. 12TFCh. 17 - Prob. 13TFCh. 17 - Prob. 14TFCh. 17 - Prob. 15TFCh. 17 - Explain why specimens should be taken aseptically,...Ch. 17 - Prob. 2CTQCh. 17 - Explain which type of ELISA can be used to...Ch. 17 - Prob. 4CTQCh. 17 - Prob. 5CTQCh. 17 - Prob. 1VCCh. 17 - From this chapter, figure 17.14. Can you explain...Ch. 17 - Prob. 1CM
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