You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo? a. Knockout b. Knockin c. Conditional knockout d. All of the choices are correct.

Question

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Answer 1

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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You are studying celiacs disease and have identified a potential gene for the disease using linkage analysis. You decide to test your hypothesis by making transgenic mice that carry a nonsense mutation in the candidate gene you have identified to see if they develop a phenotype similar to that found in Celiacs disease What sort or experimental approach are you using when you test your gene in your mouse model? a. Reverse genetic b. Quantitative genetic C. Forward genetic D.Expression analysis E. None of the above

Answer 2

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 3

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

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Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 4

Textbook Question

Chapter 17, Problem 1U

You study a gene known to be important in the early stages of heart development. Loss of the gene is also suspected to play a role in triggering lung cancer. What kind of transgenic mouse would you use to study your gene in vivo?

a. Knockout

b. Knockin

c. Conditional knockout

d. All of the choices are correct.

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

Want to see more full solutions like this?

Subscribe now to access step-by-step solutions to millions of textbook problems written by subject matter experts!

Answer 5

Textbook Question

Answer 6

Textbook Question

Answer 7

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

Answer 8

Expert Solution & Answer

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.

Conclusion

Conclusion:

Conditional knockout is a genetic engineering method that is used to eliminate a specific gene so that its effect can be studied.

Answer 9

Expert Solution & Answer

Answer 10

Expert Solution & Answer

Answer 11

Summary Introduction

Introduction:

Transgenic organisms contain a gene called transgene from different species, which is incorporated into their genetic composition through genetic engineering. The technique of genetic engineering also allows removal and change of gene as well.

Answer 12

Answer to Problem 1U

Correct answer:

Study on a gene that is known to be important in the early stages of heart development. Loss of the gene may trigger cancer. Conditional knockout is the kind of transgenic mouse that an individual would use to study that gene in vivo. Therefore, Option c. is correct.

Answer 13

Explanation of Solution

Reason for the correct statement:

Conditional gene knockout is a technique that is used to eliminate a specific gene present in the genome to study its effect on the development stages of the organism.

Option c. is given as “Conditional Knockout”.

As, “to study the effect of a gene that is known to be important in the early developmental stages of heart, conditional knockout transgenic mouse would be used” is the right answer.

Hence, Option c. is correct.

Reasons for the incorrect statements:

Option a. is given as “Knockout”.

Gene knockout is a technique that inactivates the gene, which results in loss of its functionality. Therefore, it is a wrong answer.

Option b. is given as “Knockin”.

Gene Knockin is a technique that includes replacement of the normal gene with the gene that has specific alterations. Therefore, it is a wrong answer.

Option d. is given as “All of the choices are correct”.

The study of the gene that has an important function whose loss leads to disease conditions can be done by a conditional knockout technique and not by knockout or knock-in technique. Since conditional knockout is the correct option, Option d is a wrong answer.

Hence, Options a., b., and d. are incorrect.