Concept explainers
a.
To determine: The genotypes of the parent when all their children have Rh+ blood group.
Introduction: There are two types of Rh blood groups: Rh+ (have Rh antigen) and Rh- (do not have Rh antigen). Rh factor is a point of concern when the mother has Rh- and fetus has Rh+ blood group. This condition can cause hemolytic disease of newborn baby (HDN).
b.
To determine: Whether the parents in the given case should be concerned about the risk of the occurrence of hemolytic disease to the newborn.
Introduction: There are two types of Rh blood groups: Rh+ (have Rh antigen) and Rh- (do not have Rh antigen). Rh factor is a point of concern when the mother has Rh- and fetus has Rh+ blood group. This condition can cause hemolytic disease of newborn baby (HDN).
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Human Heredity: Principles and Issues (MindTap Course List)
- Explain the role that the Ig class plays in maternal fetal incompatibility. Hint: What class is involved? Then consider the longevity of the antibody class in the mother's circulation.arrow_forwardA mom that is AB+ had a son with a B- man. Describe all possible gametes both parents could produce and list all possible blood types the baby could have, what antigens these blood types would have and what antibodies would be produced in the individual with these blood types. Lastly, explain why this baby would have a hemolytic diseasearrow_forwardPlease use instructions from above Hemophilia is an x-linked disease of the blood. What is the probability of producing an unaffected son by a father who is unaffected and a mother who is a carrier of hemophilia?arrow_forward
- A phenotypically normal man, who has a hemophiliac brother, marries a normal woman, who is not a carrier. What is the probability that any of their children will be hemophiliac?arrow_forwardGiven: Father - heterozygous for the H locus of the H antigen, heterozygous for the B locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and deuteranope Mother - heterozygous for the H locus of the H antigen, heterozygous for the A locus of the ABO blood group system, heterozygous for the D locus of the Rh blood group system, and carrier for the trait deuteranopia Task: Using the line fork method, determine the probabilities in ratio form of all possible phenotype combinations of the traits in the biological offspring of the couple. Include the solutionarrow_forwardRh factors are proteins that were first discovered in the blood of Rhesus Monkeys, but humans have them too. If you are Rh positive, it means that there are Rh type proteins in your blood. If you are Rh negative, there are no Rh type proteins in your blood. Positive is dominant over negative, so heterozygous individuals are Rh positive. Problems can arise when an Rh negative mother has a child who is Rh positive. Which of the statements will answer the following questions: Why does the mother's body attack her own baby in this situation? Why does the situation get worse for the second pregnancy? a. The mother's body sees the foreign proteins produced by her baby as a threat. She builds up antibodies against them. b. Her immune system attacks the baby, often resulting in a miscarriage. Immune suppressing drugs can be given to the mom, but then she's more likely to get sick because her body's germ fighting ability is diminished. c. The baby is delivered before the situation gets too…arrow_forward
- Woman who has blood type B positive has a daughter who is type O positive and a son who is type A negative. Rh positive is a trait that shows simple dominance over Rh negative. Which of the following is a possible phenotype for the father? a) O negative b) A negative c) AB negative d) B positivearrow_forwardThe following scenario can be seen on Ch 29 Clinical case study on Heredity (27-year-old with normal pregnancy): Mrs. Rodriguez’ blood type is type O, and her husband’s is type A. She is currently pregnant and she would like to know what type of blood her baby will have. For discussion 7 please answer the following questions: What are the genotype and phenotype of Mrs. Rodriguez? What are the genotype and phenotype of Mr. Rodriguez, given that Mr. Rodriguez’s mother has O blood type and his father has A blood type? (use Punnett Square on your worksheet to find out the genotype of Mr. Rodriquez) What is the probability that Mrs. Rodriguez’s baby will have O blood type? A? B? AB? (use Punnett Square as your worksheet) Type O =______% Type A = _____ % Type B =______% Type AB =______%arrow_forwardA woman whose blood type is A- is planning on starting a family with a B+ blood type man. Which of the following is the most accurate advice that you could give to this couple based on their blood types? They should be concerned about hemolytic disease of the newborn for all of their pregnancies . Since the woman is Rh-, she produces anti-Rh antibodies. Since the man is Rh+, the fetus in all pregnancies with this man will also be Rh+. This means that the mom?s anti-Rh antibodies will destroy fetal RBCs every time that the woman gets pregnant, thus producing a dangerous anemia to all the fetuses from all pregnancies with this man. They should be concerned about hemolytic disease of the newborn. However, problems related to this condition seldom develop during a first pregnancy, because very few fetal cells enter the maternal bloodstream then, and thus the mother?s immune system is not stimulated to produce anti-Rh antibodies. However if a future pregnancy with the…arrow_forward
- A graduating nursing student wanted to know the different blood groups and how they can be inherited. She understood that multiple allele is the inheritance pattern for ABO blood type while complete dominance for Rh factor (Rh + is dominant over Rh -). Now she wanted to know what the probable blood types from the 3 systems on her future children are. Consider the nursing student has AB, Rh negative and her current husband has O, heterozygous Rh positive. 1. What is the probability of having a child with a blood type of type O? A. 25% B. 100% C. 75% D. 50% E. 0% 2. What is the probability of having a child with a blood type of type A Rh positive? A. 1/4 B. 3/8 C. 1/2 D. 3/4 E. 1/8 3. What is the probability of having a child with a blood type of type B Rh negative? A. 3/4 B. 1/8 C. 1/4 D. 1/2 E. 3/8 4. heterozygous Rh positive. What are the possible blood types of her children? A. A Rh+, A Rh-, B Rh+, B Rh-, O Rh+, O Rh- B. A Rh+, B…arrow_forwardO. 2 Hemophilia A is an X-linked trait where blood clotting is affected due to a mutation in a clotting factor protein. Georgio has hemophilia and attends a support group where he meets Gbenga, who does not have the disease, but whose father has hemophilia. Her mother is not affected. A) If they marry, what percentage % of all their children will have hemophilia? % B) Georgio meets another woman, Maria, at the hemophilia support group. Maria also lacks the trait, but her mother has hemophilia while her father is unaffected. # 3 Would a Georgio-Maria mating provide a larger chance of having afflicted children compared to a Georgio-Gbenga mating? C) Show how you came up with your answer to B. Edit View Insert Format Tools Table 12pt ✓ 80 F3 V Paragraph ✓ $ 4 Yes or No 000 000 F4 DO LO % 5 BIUAV T² | F5 ^ MacBook Air 6 2 F6 V & 7 F7 * 8 DII F8 ( 9 DD F9 1 0 S Farrow_forwardCan two people with type A blood have a baby with type O blood? Explain your answer using a Punnett Square.arrow_forward
- Human Heredity: Principles and Issues (MindTap Co...BiologyISBN:9781305251052Author:Michael CummingsPublisher:Cengage LearningHuman Physiology: From Cells to Systems (MindTap ...BiologyISBN:9781285866932Author:Lauralee SherwoodPublisher:Cengage Learning