BIOLOGY
12th Edition
ISBN: 9781260169614
Author: Raven
Publisher: RENT MCG
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Chapter 16, Problem 1A
Summary Introduction
Introduction:
The genes coding for the proteins of a similar biochemical pathway in prokaryotes are organized in the operon. The genes in the operon are polycistronic as they are under the regulation of a single promoter. The lac (lactose) operon contains the genes coding for the
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Is each of the following statements true or false?
A. An enhancer is a type of regulatory element.
B. A core promoter is a type of regulatory element.
C. Regulatory transcription factors bind to regulatory elements.
D. An enhancer may cause the down regulation of transcription.
Transcriptional regulation often involves a regulatory protein that binds to a segment of DNA and a small effector molecule that binds to the regulatory protein. Do each of the following terms apply to a regulatory protein, a segment of DNA, or a small effector molecule?
A. Repressor
B. Inducer
C. Operator site
D. Corepressor
E. Activator
F. Attenuator
G. Inhibitor
If there is a mutation in importin that prevents it from interacting with the NLS of cargo proteins, what affect, if any, would this
have on the UPR (unfolded protein response).
A. Ran-GEF would bind to the importin promoting cargo entry into the nucleus and transcription of UPR response genes.
B. Gene regulatory protein would not be imported into the nucleus thus preventing transcription of UPR response genes
C. MRNA would not be imported into the nucleus thus preventing transcription of UPR response genes
D. Ran-GTP would not be imported to the nucleus thus preventing transcription of UPR response genes
E. No effect, these are completely unrelated processes.
Chapter 16 Solutions
BIOLOGY
Ch. 16.1 - Prob. 1LOCh. 16.1 - Prob. 2LOCh. 16.1 - Prob. 3LOCh. 16.2 - Explain how proteins can interact with base-pairs...Ch. 16.2 - Prob. 2LOCh. 16.3 - Prob. 1LOCh. 16.3 - Prob. 2LOCh. 16.3 - Explain control of gene expression in the trp...Ch. 16.4 - Prob. 1LOCh. 16.4 - Prob. 2LO
Ch. 16.4 - Prob. 3LOCh. 16.5 - Describe at least two kinds of epigenetic mark.Ch. 16.5 - Explain the function of chromatin-remodeling...Ch. 16.6 - Prob. 1LOCh. 16.6 - Prob. 2LOCh. 16.7 - Prob. 1LOCh. 16.7 - Prob. 2LOCh. 16 - Prob. 1DACh. 16 - What advantage might a bacterium gain by linking...Ch. 16 - Prob. 2IQCh. 16 - Prob. 3IQCh. 16 - In prokaryotes, control of gene expression usually...Ch. 16 - Prob. 2UCh. 16 - Prob. 3UCh. 16 - The lac operon is controlled by two main proteins....Ch. 16 - In eukaryotes, binding of RNA polymerase to a...Ch. 16 - In eukaryotes, the regulation of gene expression...Ch. 16 - In the trp operon, the repressor binds to DNA a....Ch. 16 - Prob. 1ACh. 16 - Specific transcription factors in eukaryotes...Ch. 16 - Repression in the trp operon and induction in the...Ch. 16 - Regulation by small RNAs and alternative splicing...Ch. 16 - Eukaryotic mRNAs differ from prokaryotic mRNAs in...Ch. 16 - In the cell cycle, cyclin proteins are produced in...Ch. 16 - A mechanism of control in E. coli not discussed in...Ch. 16 - You have isolated a series of mutants affecting...Ch. 16 - Examples of positive and negative control of...Ch. 16 - What forms of eukaryotic control of gene...Ch. 16 - The number and type of proteins found in a cell...
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- Two different types of gene regulatory elements are DNA sequence and protein-based. Which of the following describes them, respectively? a. one blocks translation, the other blocks transcription b. The first is an aporepressor, the second is a promoter c. The first is an enhancer, the second is a repressor d. The first is a activator, the second is a an attenuator e. one is an activist, the other is a protestorarrow_forwardAfter treating cells in tissue culture with an HDAC inhibitor, which of the following is the most likely outcome? A. Repression of transcription B. Promoter methylation C. Enhanced splicing D. Activation of transcription E. Depends on the cell typearrow_forwardWhich of the following is false regarding the role of mediator complex in eukaryotic transcription initiation? a. Mediator complex interacts with RNA pol II b. Mediator binds to upstream enhancer sequences c. Mediator interacts with general transcription factors d. Mediator interacts with transcriptional activators e. All of the above are true about the mediator complexarrow_forward
- All genes regulated by PKA contain a cis-acting DNA sequence that binds to the phosphorylated form of a transcription factor called (choose one answer) a. CREB. b. C-Jun. c. beta-catenin. d. TCF.arrow_forwardAlternative RNA splicing a. is a mechanism for increasing the rate of transcription. b. can allow the production of proteins of different sizes from a gene. C. can allow the production of similar proteins from different RNAS. d. increases the rate of transcription. e. is due to the presence or absence of particular snRNAs.arrow_forwardDefine the following terms: a. promoter b. consensus sequence c. operon d. chromatin-remodeling complex e. general transcription factorsarrow_forward
- In E. coli, induction in the lac operon and repression in the trp operon are both examples of a. negative control by a repressor. b. positive control by a repressor. c. negative control by an activator. d. positive control by a repressor.arrow_forwardE. coli are grown on a medium containing lactose. Once glucose is added to the medium, the bacteria stop fermenting lactose. Which of the following BEST explains the observed effect? A. Cellular levels of cAMP are lowB.Glucose is bound to the promoter C. Repressor protein is bound to the operator D. Repressor protein is bound to the promoterarrow_forwardHow does reverse methylation affect gene expression? Select one: o a. The gene is turned off, but still expresses a protein product. b. The gene becomes transcriptionally silent. c. There is no effect on the gene. d. The gene is hyperactive resulting in a gain of function. e. The gene expresses the wrong protein. Clear my choice How do microRNAs regulate epigenetic mechanisms during development? Select one: o a. MicroRNAs function as gene repressors b. You only find microRNAS in epigenetic and cancer cells c. MicroRNAs function as gene activators d. MicroRNAS regulate methylation on the DNA sequences of embryos e. Researchers find that when microRNAs are present the effects of epigenetic modifications are 50% greater Clear my choicearrow_forward
- Transcriptional repressor proteins (e.g., lac repressor), antisense RNA, and feedback inhibition are three different mechanisms that turn off the expression of genes and gene products. Which of these three mechanisms will be most effective in each of the following situations? A. Shutting down the synthesis of a polypeptide B. Shutting down the synthesis of mRNA C. Shutting off the function of a protein For your answers to parts A–C that list more than one mechanism, which mechanism will be the fastest or the most efficient?arrow_forwardWhich of these is used in the transcription of all genes? Choose all correct answers. A. Core promoter B. Proximal promoter C. Distal promoter D. General Transcription Factors E. Regulatory Transcription Factorsarrow_forwardIf CAP is bound to the Promoter of the Lac Operon and the repressor protein is not bound to the operator, which of the following is true: a.Glucose Levels are low & Lactose is absent b.Glucose is absent & Lactose is present c.cAMP is low & Lactose is Absent d.Glucose and Lactose are Present e.cAMP is low & Lactose is presentarrow_forward
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