Genetics: A Conceptual Approach
Genetics: A Conceptual Approach
6th Edition
ISBN: 9781319050962
Author: Benjamin A. Pierce
Publisher: W. H. Freeman
Question
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Chapter 15.3, Problem 31AQP

(a)

Summary Introduction

To determine:

The potential effect of a mutation in the part of tRNA genes that encodes the acceptor stem.

Introduction:

Transfer RNA is an important component of translation machinery and it has a three-dimensional shape called Cloverleaf model. The binding of amino acid to transfer RNAs  (tRNAs) is the most important stage in the translation process. All  tRNAs contain CCA sequence at the 3' end, and the carboxyl group of the amino acid is coupled to the adenine nucleotide at the 3' end of the tRNA. Aminoacyl-tRNAsynthetase is a set of an enzyme that provides specificity between an amino acid and its tRNA.

(b)

Summary Introduction

To determine:

The potential effect of a mutation in the part of tRNA genes that encodes the anticodon.

Introduction:

Transfer RNA is an important component of translation machinery and it has a three-dimensional shape called Cloverleaf model. The binding of amino acid to transfer RNAs  (tRNAs) is the most important stage in the translation process. All  tRNAs contain CCA sequence at the 3' end, and the carboxyl group of the amino acid is coupled to the adenine nucleotide at the 3' end of the tRNA. Aminoacyl-tRNAsynthetase is a set of an enzyme that provides specificity between an amino acid and its tRNA.

(c)

Summary Introduction

To determine:

The potential effect of a mutation in the part of tRNA genes that encodes one of the red nucleotide positions.

Introduction:

Transfer RNA is an important component of translation machinery and it has a three-dimensional shape called Cloverleaf model. The binding of amino acid to transfer RNAs  (tRNAs) is the most important stage in the translation process. All  tRNAs contain CCA sequence at the 3' end, and the carboxyl group of the amino acid is coupled to the adenine nucleotide at the 3' end of the tRNA. Aminoacyl-tRNAsynthetase is a set of an enzyme that provides specificity between an amino acid and its tRNA.

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