Microbiology: An Introduction (13th Edition)
13th Edition
ISBN: 9780134605180
Author: Gerard J. Tortora, Berdell R. Funke, Christine L. Case, Derek Weber, Warner Bair
Publisher: PEARSON
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Textbook Question
Chapter 15, Problem 4R
Explain how drugs that bind each of the following would affect pathogenicity:
- a. iron in the host’s blood
- b. Neisseria gonorrhoeae fimbriae
- c. Streptococcus pyogenes M protein
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Different strains of Streptococcus pyogenes have different virulence factors, giving these microbes much versatility. Virulence factors include which of the following? Choose one or more:
A.A capsule that, when thick, will help the organism avoid phagocytosis by macrophages
B.A cell wall containing lipoteichoic acid, thought to facilitate adherence to pharyngeal epithelial cells
C.Enzymes that lyse blood cells (streptolysins)
D.The production of several endotoxins called streptococcal pyogenic endotoxins (SPEs)
a.) The transmission of this disease can occur through an arthropod vector.
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Hepatitis A
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H. influenzae
b.) Consumption of contaminated food or water can lead to infection with:
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HIV
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c.) This pathogen is a common inhabitant of the human intestines and can cause urinary tract infections, particularly in patients with urinary catheters.
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Neisseria meningitidis
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Mycobacterium leprae
Which of the following virulence factors among A-D is correctly matched with its definition or characterization?
A) O Invasins: pathogen proteins that prevent opsonization of the pathogen
B) O Phase variation: allows pathogen to switch between different forms of an extracellular antigen (e.g., flagellum)
C) O Protein A. a microbial factor that allows for attachment, typically a surface protein or surface glycoprotein
D) O Prevention of lysosome:phagosome fusion mechanism employed by an extracellular pathogen
E) OM protein, Opa protein: enzymes that interfere with the functioning of antibodies
Chapter 15 Solutions
Microbiology: An Introduction (13th Edition)
Ch. 15 - Compare pathogenicity with virulence.Ch. 15 - How are capsules and cell wall components related...Ch. 15 - Prob. 3RCh. 15 - Explain how drugs that bind each of the following...Ch. 15 - Prob. 5RCh. 15 - Prob. 6RCh. 15 - Prob. 7RCh. 15 - Which of the following genera is the most...Ch. 15 - How can viruses and protozoa avoid being killed by...Ch. 15 - Prob. 10R
Ch. 15 - The removal of plasmids reduces virulence in which...Ch. 15 - Prob. 2MCQCh. 15 - Prob. 3MCQCh. 15 - All of the following can occur during bacterial...Ch. 15 - The ID50 for Campylobacter sp. is 500 cells; the...Ch. 15 - Prob. 6MCQCh. 15 - A drug that binds to mannose on human cells would...Ch. 15 - The earliest smallpox vaccines were infected...Ch. 15 - Prob. 9MCQCh. 15 - Which of the following statements is true? a. The...Ch. 15 - Prob. 1ACh. 15 - Prob. 2ACh. 15 - Prob. 3ACh. 15 - How do each of the following strategies contribute...Ch. 15 - On July 8, a woman was given an antibiotic for...Ch. 15 - Explain whether each of the following examples is...Ch. 15 - Cancer patients undergoing chemotherapy are...
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