Interpretation:
The retrosynthetic route for synthesis of
Concept introduction:
Electrophiles are electron deficient species that have positive or partially positive charge. Lewis acids are electrophiles that accept electron pair.
Nucleophiles are electron rich species that have negative or partially negative charge. Lewis bases are nucleophiles that donate electron pair.
Free radical is an atom, molecule, or ion that has unpaired electrons, which makes it highly chemically reactive.
Substitution reaction: A reaction in which one of the hydrogen atoms of a hydrocarbon or a functional group is substituted by any other functional group is called substitution reaction.
Elimination reaction: A reaction in which two substituent groups are detached and a double bond is formed is called elimination reaction.
Addition reaction: It is the reaction in which unsaturated bonds are converted to saturated molecules by the addition of molecules.
Retrosynthesis is a technique in which the
A target molecule is deconstructed into readily available starting materials by retro synthesis. The process involves imaginary breaking of bonds by the conversion of one functional group into another.
Nitrating mixture (concentrated sulfuric acid and nitric acid).
Oxidation of methyl group by potassium permanganate gives
Friedel Craft’s reaction with chlorine in ferric chloride gives chloro substitution, meta to nitro group.
Methyl group is ortho/para directing group.
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Organic Chemistry
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- The pKa of phenol is 10.0 and the pKa of para-nitrophenol is 7.2. Given this information, one knows that The conjugate base of para-nitrophenol must be less stable than the conjugate base of phenol The conjugate acid of para-nitrophenol must be more stable than the conjugate base of phenol The conjugate base of para-nitrophenol must be more stable than the conjugate base of phenol Both acids are basesarrow_forward1- Convert Aniline to Diazonium Salt 2- Convert Aniline to iodobenzene 3- Convert Aniline to carboxylic acidarrow_forwardWhat reactions and reagents can be used to make phenol from benzene if electrophilic aromatic substitution reactions are excluded and benzene is the only source of carbon?arrow_forward
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