Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 15, Problem 21P
Interpretation Introduction
Interpretation:
The function for the amino acid derivative, arginine phosphateneeds to be proposed.
Concept introduction:
The organic compounds that contain
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Pro-Ser-Ala-Phe-Glu. Draw this peptide at pH 7 and include its stereochemistry.
Part C
Using the values of pKas in the table below, calculate the pI for DTLH.
Properties of some amino acids found in proteins
Name
Aspartic
acid
Abbreviations: 1- and 3-
letter codes
D, Asp
Histidine
H, His
Leucine
L, Leu
Threonine T, Thr
ΓΙ ΑΣΦ
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pKa of a-COOH pKa of a-NH3+ pKa of lonizing
Group
Group
Side Chain
Express your answer to two significant figures.
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2.1
1.8
2.4
2.6
?
9.8
9.2
9.6
10.4
3.9
6.0
Rotation about the peptide bond in glycylglycine ishindered. Draw the resonance forms of the peptide bondand explain why.
Chapter 15 Solutions
Biochemistry
Ch. 15 - Prob. 1PCh. 15 - Prob. 2PCh. 15 - Prob. 3PCh. 15 - Prob. 4PCh. 15 - Prob. 5PCh. 15 - Prob. 6PCh. 15 - Prob. 7PCh. 15 - Prob. 8PCh. 15 - Prob. 9PCh. 15 - Prob. 10P
Ch. 15 - Prob. 11PCh. 15 - Prob. 12PCh. 15 - Prob. 13PCh. 15 - Prob. 14PCh. 15 - Prob. 15PCh. 15 - Prob. 16PCh. 15 - Prob. 17PCh. 15 - Prob. 18PCh. 15 - Prob. 19PCh. 15 - Prob. 20PCh. 15 - Prob. 21PCh. 15 - Prob. 22PCh. 15 - Prob. 23PCh. 15 - Prob. 24PCh. 15 - Prob. 25PCh. 15 - Prob. 26PCh. 15 - Prob. 27PCh. 15 - Prob. 28PCh. 15 - Prob. 29PCh. 15 - Prob. 30PCh. 15 - Prob. 31PCh. 15 - Prob. 32PCh. 15 - Prob. 33PCh. 15 - Prob. 34PCh. 15 - Prob. 35PCh. 15 - Prob. 36PCh. 15 - Prob. 37PCh. 15 - Prob. 38PCh. 15 - Prob. 39P
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- Predict the direction of migration for the following amino acids in solutions of the specified pH. Write Isoelectric, if no migration occurs: Lys at pH=12 (pk values: 2.2; 9.2; 10.8) Glu at pH= 2.0 (pk values: 2.1; 9.5; 4.1) Leu at pH= 6.0 (pk vaues: 2.3; 9.7)arrow_forwardtide c lirectir as ques ar to t synthr direct s, the secon aft 43. Peptide bond formation has a positive AG. What is ATP's role in making protein synthesis favorable?arrow_forwardInstruction for the said activity: Write the structure of each of the following peptide at pH7 and identify how many peptide bond in each number. d. Alanyl-phenylalanine- aspartate- cysteine e. Threonyl- Isoleucyl-methionyl- leucine f. Lysyl-alanine -Phenylalanyl-tyrosyl- serinearrow_forward
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