BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
3rd Edition
ISBN: 9781260670929
Author: Hoefnagels
Publisher: MCG CUSTOM
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Chapter 15, Problem 1WIO
If you were developing a new “broad-spectrum” antibiotic to kill a wide variety of bacteria, which cell structures and pathways would you target? Which of those targets also occur in eukaryotic cells, and why is that important?
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If you were developing a new “broad-spectrum” antibiotic to kill a widevariety of bacteria, which cell structures and pathways would you target?Which of those targets also occur in eukaryotic cells, and why is thatimportant? How would your strategy change if you were designing a new“narrow-spectrum” antibiotic active against only a few types of bacteria?
Most antibacterial drugs disrupt or destroy prokaryotic cellular structures or processes that are different than those of eukaryotic cells or may not even be present in eukaryotic cells. List and describe at least three prokaryotic cellular features that could be targeted to inhibit or kill a bacterial pathogen without harming its eukaryotic host.
What is the best explanation for why a bacteriostatic treatment might be chosen over a bacteriocidal treatment? Bacteriostatic treatments will eliminate all bacteria while bacteriocidal treatments will only eliminate a portion of the bacteria. Bacteriostatic treatments typically have lower toxicity to the host when compared to bacteriocidal treatments. Bacteriostatic treatments will prevent all bacterial growth, while bacteriocidal treatments will permit some bacterial growth. Bacteriostatic treatments are typically more costly than bacteriocidal treatments.
Chapter 15 Solutions
BIOLOGY:THE ESSENTIALS (LL) W/CONNECT
Ch. 15.1 - Prob. 1MCCh. 15.1 - What we can learn from simulations of early Earth?Ch. 15.1 - Prob. 3MCCh. 15.1 - Prob. 4MCCh. 15.2 - Prob. 1MCCh. 15.2 - Without looking at figure 15.9, sketch the...Ch. 15.2 - Prob. 3MCCh. 15.2 - In what ways bacteria and archaea are essential to...Ch. 15.2 - Prob. 5MCCh. 15.3 - Prob. 1MC
Ch. 15.3 - List a logical sequence of evolutionary events...Ch. 15.4 - Prob. 1MCCh. 15.4 - Prob. 2MCCh. 15.4 - Prob. 3MCCh. 15.5 - Prob. 1MCCh. 15.5 - Prob. 2MCCh. 15.5 - Prob. 3MCCh. 15.5 - How do fungi benefit humans?Ch. 15.5 - Prob. 5MCCh. 15 - Prob. 1MCQCh. 15 - Prob. 2MCQCh. 15 - Prob. 3MCQCh. 15 - Prob. 4MCQCh. 15 - Prob. 5MCQCh. 15 - If you were developing a new broad-spectrum...Ch. 15 - Prob. 2WIOCh. 15 - Prob. 3WIOCh. 15 - Prob. 4WIOCh. 15 - Prob. 5WIOCh. 15 - Prob. 1SLCh. 15 - Review the Survey the Landscape figure in the...Ch. 15 - Prob. 2PIT
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- The ribosome is the target for many important antibiotics. These drugs must discriminate between bacterial and eukaryotic ribosomes to achieve drug specificity and toxicity. For the two common antibiotics below, what is their mechanism of action and why are they more toxic to bacteria than eukaryotes? a) Tetracycline b) Erythromycinarrow_forwardWhich of the following is/are evidence that mitochondria and bacteria are descendants of bacteria? (Select all that apply.) a) The DNA structure of mitochondria and chloroplasts is similar to that of bacteria b) The DNA sequence of mitochondria and chloroplasts is similar to that of bacteria c) Mitochondria and chloroplasts have their own genomes that are not enclosed in a nuclear envelope. d) MItochondria and chloroplasts have their own ribosomes.arrow_forwardIdentify the single most correct answer: a) Ribosome is an organelle found in both prokaryotes and eukaryotes. Ob) During conjugation a naked DNA molecule found in the surroundings gets into bacteria. c) Spontaneous mutation cannot result in the production of an altered protein. Od) Gene transfer from one species of bacteria to another (donor to recipient) represents horizontal gene transfer.arrow_forward
- In order to determine the genetic material of a T2 phage, Alfred Hershey and Martha Chase conducted experiments using T2 phages that infected bacteria. In one treatment, they grew phages with radioactive sulfur. In another treatment, they grew phages with radioactive phosphorous. They allowed both types of phages to infect bacterial cells. After infection, they found that only bacteria infected with phages grown with radioactive phosphorous showed any radioactivity. Why did they use radioactive sulfur and phosphorous for this experiment? * O Sulfur is part of the DNA molecule but not part of a protein molecule. Sulfur and phosphorous are some of the most reactive molecules and are easily traced. Sulfur and phosphorous are able to survive the centrifuge, a crucial component of the experiment. O Phosphorous is part of the DNA molecule but not part of a protein molecule.arrow_forwardBacterial species that are harmful, as well as others that are beneficial, are found living in the human body. To slow the rate of developing antibiotic resistance in bacteria, physicians are being encouraged to use "narrow-spectrum" antibiotics- those that target only a few bacterial types. How can the information learned by antibiotic sensitivity testing be used by physicians who must choose antibiotics that inhibit the growth of bacteria causing disease but that do not interfere with beneficial bacteria?arrow_forwardAntibiotic resistant bacteria have become a major concern for many public health officials. Widespread use of antibiotics has created an evolutionary pressure on infectious bacteria to develop immunity to these medications. The result is an increase in antibiotic resistant microbes, particularly in settings where antibiotics are commonly used, such as hospitals. One strategy public health officials have devised to counteract these infectious microbes is "antibiotic cycling” where specific antibiotics are withdrawn from the market for a period of several years, then reintroduced as another antibiotic is withdrawn. How would this strategy help limit antibiotic resistance? A. It is impossible for a bacterium to maintain resistance to two antibiotics at once B. When a given antibiotic is not in use, it is an evolutionary disadvantage to carry the unneeded gene C. If a specific antibiotic is removed from the market it is possible to substitute with a related antibiotic such as…arrow_forward
- How can i explain my answers in depth in microbology for example this question: Assume that there are horizontal gene transfers between two completely different bacterial species. In one case it is a plasmid that is transferred via conjugation, in the other case it is a part of the bacterial chromosome that is transferred via transformation. In which of the two cases is it most likely that the transferred DNA will remain and be able to function in the recipient cells? Explain the biological background to your answer . How do I break down the question so I answer it fullyarrow_forwardThe most selectively toxic antibacterial agents are those that interfere with bacterial cell wall synthesis. This is because ________. Group of answer choices bacterial cell wall synthesis is easily inhibited whereas eukaryotic cell wall synthesis is more resistant to the actions of the drugs bacterial cell walls have a unique structure not found in eukaryotic host cells eukaryotic cells do not take up the drugs eukaryotic cells inactivate the drugs before they can do any damagearrow_forward25) Identify the most correct choice: a) ribosomes are the membrane bound organelles responsible for making proteins from RNAs. b) In gene therapy, Agrobacterium is the bacteria that transfers genetic material into the human cells that contain the mutated gene. c) spectrophotometer analysis can be used to detect the concentration of the dead cells in a solution only and not those that are living. d) None of the above.arrow_forward
- Microbiologists have announced the discovery of over 30 new species of bacteria that thrive between the teeth and gums of humans. The bacteria could not be grown in the researcher's laboratories, nor were any of them ever observed via and kind of microscopy. If they couldn't culture them or see them, how could the researchers know they discovered a new species? If they couldn't examine the cells for the presence of a nucleus, how did they determine that the organisms were prokaryotes and not eukaryotes?arrow_forwardIn terms of microbial pathogenicity, molecular Koch's postulates are a set of experimental criteria that show: A microbe is the aetiological agent of a disease A gene encodes a product that contributes to disease A gene encodes a product that contributes to immunity to a disease A mutation does not contribute to diseasearrow_forwardAntibotic/drug resistance in bacteria results from mutations induced by the anitbiotic which enhance fitness of the bacteria ensuring their survival. a) True b) Falsearrow_forward
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