Chapter 15, Problem 15.43QP

Computational Problems

15.43 The aqueous reaction

$L-glutamate+pyruvate\rightleftarrows \alpha -ketoglutarate+L-alanine$

is catalyzed by the enzyme l-glutamate–pyruvate aminotransferase. At 300 K, the equilibrium constant for the reaction is 1.11. Predict whether the forward reaction will occur if the concentrations of the reactants and products are [l-glutamate] = 3.0 × 10⁻⁵ M, [pyruvate] = 3.3 × 10⁻⁴ M, [α-ketoglutarate] = 1.6 × 10⁻² M, and [l-alanine] = 6.25 × 10⁻³ M.