Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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Chapter 13, Problem 30P
Interpretation Introduction
Interpretation:
The recordings of ion movement that look like in the syndrome needs to be explained biochemically.
Concept introduction:
Acetylcholine act as a neurotransmitter which means it sends messages or chemicals from one cell to another cell of the body. Acetyl-cholinesterase helps in stopping the excitation of a nerve cell after the transmission of impulse or in other words, we can say that this enzyme causes rapid hydrolysis of acetylcholine.
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Problems 14 and 15: some of the exponents are unclear. Here they are:
14. Calculate vi and the degree of inhibition caused by a competitive inhibitor under the following conditions:(a) [S]=2x10-3 Mand[I]=2x10-3 M(b) [S]=4x10-4 Mand[I]=2x10-3 M
(c) [S]=7.5x10-3 Mand[I]=10-5 MAssume that Km = 2 x 10-3 M, Ki = 1.5 x 10-4 M
and Vmax = 270 nmoles x liter-1 x min-1.The degree of inhibition is the percent of the uninhibited velocity reached in the presence of the inhibitor.
15. (a) What concentration of competitive inhibitor is required to yield 75% inhibition at a substrate concentration of 1.5 x 10-3 M if Km =2.9x10-4 M and Ki =2x10-5 M? (b)Towhatconcentration must the substrate be increased to reestablish the velocity at theoriginal uninhibited value?
Please ASAP. THanku.
QS 4 Why is the resting membrane potential a negative value? And how do you determine resting membrane potential?
Biochemical events in the synthesis of ATP:
I. Subunits of ATP synthase chages in conformation and twists/rotates as H+ moves through it
II. H+ gradient is the driving force (through the ATP synthase) to form ATP from ADP + Pi.
III. H+ moving across the membrane through ATP synthase rotates its ring of c subunits
II and III only
I, II, III
I and II only
I and III only
Chapter 13 Solutions
Biochemistry
Ch. 13 - Prob. 1PCh. 13 - Prob. 2PCh. 13 - Prob. 3PCh. 13 - Prob. 4PCh. 13 - Prob. 5PCh. 13 - Prob. 6PCh. 13 - Prob. 7PCh. 13 - Prob. 8PCh. 13 - Prob. 9PCh. 13 - Prob. 10P
Ch. 13 - Prob. 11PCh. 13 - Prob. 12PCh. 13 - Prob. 13PCh. 13 - Prob. 14PCh. 13 - Prob. 15PCh. 13 - Prob. 16PCh. 13 - Prob. 17PCh. 13 - Prob. 18PCh. 13 - Prob. 19PCh. 13 - Prob. 20PCh. 13 - Prob. 21PCh. 13 - Prob. 22PCh. 13 - Prob. 23PCh. 13 - Prob. 24PCh. 13 - Prob. 25PCh. 13 - Prob. 26PCh. 13 - Prob. 27PCh. 13 - Prob. 28PCh. 13 - Prob. 29PCh. 13 - Prob. 30PCh. 13 - Prob. 31PCh. 13 - Prob. 32P
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