EBK ORGANIC CHEMISTRY-PRINT COMPANION (
EBK ORGANIC CHEMISTRY-PRINT COMPANION (
4th Edition
ISBN: 9781119776741
Author: Klein
Publisher: WILEY CONS
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Chapter 11, Problem 31ASP
Interpretation Introduction

Interpretation: To identify the best reaction sequence that can accomplish the transformation as given.

Concept introduction: Elimination reaction by using a strong, sterically hindered base ( tBuOK ) gives the Hofmann alkene product. The Hofmann rule states that the major alkene product is the least substituted product during an elimination reaction.

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Indicate the sequence of reactions necessary to carry out the following transformations
Synthesize the products by drawing out reagents and intermediates along the way.
Draw the reactant of the following reaction sequence.
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How to Design a Total Synthesis; Author: Chemistry Unleashed;https://www.youtube.com/watch?v=9jRfAJJO7mM;License: Standard YouTube License, CC-BY