Biology: Science for Life with Physiology (6th Edition) (Belk, Border & Maier, The Biology: Science for Life Series, 5th Edition)
Biology: Science for Life with Physiology (6th Edition) (Belk, Border & Maier, The Biology: Science for Life Series, 5th Edition)
6th Edition
ISBN: 9780134555430
Author: Colleen Belk, Virginia Borden Maier
Publisher: PEARSON
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Chapter 10, Problem 2AAATB
Summary Introduction

To write:

The effects on a cell that undergoes a mutation to its RNA polymerase gene.

Introduction:

The RNA is a type of nucleic acid that is formed from ribose sugar. There are three types of RNA molecules. These are “tRNA, mRNA, and rRNA”. The RNA polymerase is an important enzyme.

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Gene Expression: 14) Look at the diagram: a) For each of the molecules in the diagram, identify what type of molecule they are, and label their ends (3',5',N,C). b) For each arrow, name the process and identify the major enzymes involved. c) Where do each of these activities take place in a bacterial cell? In a eukaryotic cell? Draw a picture if it helps you explain it.
(b) (c) Point mutations in multiple tumor suppressor proteins have been linked to cancer. For example changes in the gene for adenomatous-polyposis-coli protein (APC gene) may result in colorectal cancer. Consider the following DNA sense strand. 3-TAC CGG TTG TGA AGC TGA ATC-5' Derive the mRNA molecule from the given DNA strand sequence above, paying attention to the polarity of the molecule. (i) (ii) (iii) (iv) Write down the polypeptide chain sequence arising from the mRNA molecule of the question above, using the table of the genetic code (Table Q1 overleaf) and indicate the C- and the N-terminus of the peptide chain. Point mutations of a cytosine (C) often lead to the dysfunction of the APC protein. Write down all possible polypeptide chains that can result from all possible DNA mutations of cytosines, disregarding a mutation in the MET/START and STOP codons. Specify which of the point mutations identified in (d) are redundant? For the given tRNA for Thrombin (Thr) write down all…
Process by which the DNA sequences encoding exons are exchanged and reordered through genetic recombination between DNA sequences encoding introns. Group of answer choices a)RNA editing b)Exon Definition c) Exon Shuffling  d)Transesterification
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