Concepts of Biology
1st Edition
ISBN: 9781938168116
Author: Samantha Fowler, Rebecca Roush, James Wise
Publisher: OpenStax College
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Chapter 10, Problem 13CTQ
Identify a possible advantage and a possible disadvantage of a genetic test that would identify genes in individuals that increase their probability of having Alzheimer’s disease later in life.
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Chapter 10 Solutions
Concepts of Biology
Ch. 10 - Figure 10.7 Why was Dolly a Finn-Dorset and not a...Ch. 10 - n gel electrophoresis of DNA, the different bands...Ch. 10 - In the reproductive cloning of an animal, the...Ch. 10 - What carries a gene from one organism into a...Ch. 10 - What is a genetically modified organism (GMO)? a....Ch. 10 - What is the role of Agrobacterium tumefaciens in...Ch. 10 - What is the most challenging issue facing genome...Ch. 10 - Genomics can be used in agriculture to: a....Ch. 10 - What kind of diseases are studied using...Ch. 10 - What is the purpose and benefit of the polymerase...
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- The role of the TPMT genotype in response to treatment emphasizes the importance of pharmacogenomics. What changes in treatment would be recommended for someone homozygous recessive for TPMT, compared to someone that is homozygous dominant?arrow_forwarda. It is possible to perform DNA fingerprinting withSNPs instead of SSRs as DNA markers, but ingeneral you would need to examine more SNPmarkers than the 13 SSRs used in the CODIS database to be sure of a match. Explain why.b. DNA fingerprinting has been used to verify pedigrees of valuable animals such as show dogs, racinggreyhounds, and thoroughbred horses. However, thetechnology is much harder to apply in these casesthan it is in forensic applications for humans. In particular, many more DNA markers must be examinedin domesticated animals to establish the identity orclose familial relationship of two DNA samples.Why would you need to look at more polymorphicloci in these animals than you would in humans?arrow_forwardWhich sequence variations are identified by NGS and in which format they are store Discuss in details the software used to identify the effect or nature of these variants. How this information can be used for personalized medicine.arrow_forward
- What Genetic Conditions Are Candidates for Treatment by GeneTherapy?arrow_forwardBriefly explain this Statement "Treatment for the genetic disorders by using gene therapy " Please answer at your own words, please (400-500 words).arrow_forwardMake a list of the benefits that may arise from genetic testing as wellas possible negative consequences. Discuss the items on your list.arrow_forward
- Mention the advantages and the challenges of using SNP markers in DNA typing.arrow_forwardWhat are the importance of dosage forms? Explain your answerarrow_forward1. a) If you were at risk of a fatal disease such as Huntington’s disease and only the 95% accurate preliminary genetic test was available, would you take the test? After all, 95% of the time the test would tell you whether you would eventually get Huntington’s disease or whether you did not have to worry about getting this disease. b) The linkage distance between the DNA sequence used in the test and the actual Huntington’ disease locus was 5%. In a large sample of the Venezuelan family, what percentage of people would inherit the DNA sequence but not the Huntington’s allele (i.e. be a false positive test for Huntington’s)? What percentage of that large Venezuelan family would not inherit the DNA sequence but would inherit the Huntington’s allele (i.e., be a false negative test for Huntington’s)?arrow_forward
- It has been suggested that it would make the study of human diseases easier if cloned transgenic animals were produced that carried faulty versions of human genes (e.g., the gene that causes cystic fibrosis). a. Why would such animals be useful in medical research? : b. What ethical questions are raised by the creation of such transgenic animals?arrow_forwardWhat is DNA fingerprinting? Mention its application.arrow_forwardA 45-year-old woman undergoes genetic testing and discovers that she is at high risk for developing colon cancer and Alzheimer disease. Because her children have 50% of her genes, they may also be at an increased risk for these diseases. Does she have a moral or legal obligation to tell her children and other close relatives about the results of her genetic testing?arrow_forward
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