Microbiology: Principles and Explorations
9th Edition
ISBN: 9781118743164
Author: Jacquelyn G. Black, Laura J. Black
Publisher: WILEY
expand_more
expand_more
format_list_bulleted
Concept explainers
Videos
Textbook Question
Chapter 1, Problem 5CTQ
The completion of chromosomal mapping and sequencing of genes in the Human Genome Project has been one of humanity’s greatest accomplishments, yet it really serves as just the beginning for a new era of genomic science.
- (a) Can you think of new burgeoning fields of science that will result from the newly acquired sequencing data?
- (b) Antibiotics are effective because of their selective killing of bacterial and not animal cells. Can you think of ways in which comparing bacterial genomes to the human genome might result in additional cures of bacterial infections/diseases?
Expert Solution & Answer
Want to see the full answer?
Check out a sample textbook solution
Students have asked these similar questions
Scientists have reportedly isolated short fragments of DNA from fossilized dinosaur bones hundreds of millions of years old. The technique used to isolate this DNA is the polymerase chain reaction, which is capable of amplifying very small amounts of DNA a millionfold. Critics have claimed that the DNA isolated from dinosaur bones is not purely of ancient origin, but instead has been contaminated by DNA from present-day organisms such as bacteria, mold, or humans. What precautions, analyses, and control experiments could be carried out to ensure that DNA recovered from fossils is truly of ancient origin?
Answer all of the following questions
a) Define the following terms: biotechnology, Plasmid,Genetic engineering and Transformation
b) List two types of medical products that can be produced using DNA tech-
nology
c) Relate bioethics to the continued development of genetic engineering
techniques.
d) Describe two major goals of the Human Genome Project.
e) Distinguish between proteomics and genomics.
f) Outline the different applications of biotechnology
g) List some techniques of genetic engineering.
h) Delineate the transgenic organisms and their significance.
i) Explain the procedure for the following
PCR, Gel electrophpresis and Gene therapy
j) Describe human genome project and its main goals.
k) Discuss the drastic environmental impacts of oil spills and how the mi-
crobes like bacteria can help mitigate the problem.
l) Give an account of significance of transgenic organisms in food industry.
m) Describe the uses of DNA finger printing.
n) What is gene cloning?
o) Elaborately…
1) One of the first studies extracted all the DNA from a biofilm in an acid mine drainage in northern California in 2004. Then cloned the DNA in E. coli, sequenced all of the cloned fragments and then attempted to reconstruct the genomes of the different individuals in the population. This approach is an example of what?
-Transcriptomics
-Genomics
-Metatranscriptomics
-Metagenomics
-Proteomics
Chapter 1 Solutions
Microbiology: Principles and Explorations
Ch. 1 - List three reasons to study microbiology.Ch. 1 - What is the difference between microbiology and...Ch. 1 - Prob. 1.3SCCh. 1 - List five bacterial diseases and five viral...Ch. 1 - Prob. 2.1SCCh. 1 - State the germ theory of disease. Try to think of...Ch. 1 - How did Pasteurs experiment with swan-necked...Ch. 1 - Why was the French microbiologists method of broth...Ch. 1 - What were the scientific contributions of Jenner,...Ch. 1 - Prob. 3.2SC
Ch. 1 - What is the Human Genome Project? How has...Ch. 1 - Prob. 1CCSCh. 1 - Prob. 1CTQCh. 1 - Can you think of some reasons why it might be hard...Ch. 1 - As often happens in science, one observation or...Ch. 1 - It is likely that others beside Anton van...Ch. 1 - The completion of chromosomal mapping and...Ch. 1 - Prob. 6CTQCh. 1 - Prob. 1SQCh. 1 - Conclusive evidence of thriving microbial life has...Ch. 1 - Which of the following is not true? (a) A single...Ch. 1 - Which is false regarding Archaea? (a) They lack a...Ch. 1 - Why are microbes important to study and how are...Ch. 1 - Prob. 6SQCh. 1 - Prob. 7SQCh. 1 - Animals such as worms and ticks are too large to...Ch. 1 - Prob. 9SQCh. 1 - Prob. 10SQCh. 1 - What triggered the development and establishment...Ch. 1 - Prob. 12SQCh. 1 - Prob. 13SQCh. 1 - The biggest obstacle in the acceptance and...Ch. 1 - Match the following terms to the appropriate...Ch. 1 - Prob. 16SQCh. 1 - Prob. 17SQCh. 1 - Prob. 18SQCh. 1 - Describe the contributions of the following...Ch. 1 - Prob. 20SQCh. 1 - Prob. 21SQCh. 1 - Prob. 22SQ
Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.Similar questions
- Jackson Wang is a biologist working with the genetics of a thermophilic bacterium. He cloned a heat shock gene from the bacteria for further analysis. After cloning, he isolated the plasmid carrying his gene of interest for sequencing. Jackson finally received the nucleotide sequence of his gene. Explain in detail how he could verify whether the nucleotide sequence matches his gene of interest using the bioinformatics databases available.arrow_forwardIn 1995, Hamilton Smith, Craig Venter and co-workers published the first complete genome sequence of a self-sustaining organism, that of the bacterium Haemophilus influenzae. Analysis of the genome sequence revealed that the organism does not have a gene that could encode a telomerase enzyme. What is the potential evolutionary consequence of this? Explain your answer.arrow_forwardThe first publications describing the successful production and intracellular replication of recombinant DNA appeared in the early 1970’s. Since then, there is a long list of breakthroughs achieved by recombinant DNA technology. But which one of the following are NOT on that list? Select more than one answer ifneeded. a) Recombinant Factor VIII protein for the treatment of hemophiliacs b) Positional cloning of over 100 human disease genes c) Bacteria producing human insulin for the treatment of diabetic patients d) Reproductive cloning of over a dozen humansarrow_forward
- Imagine that there is an E. coli outbreak in your area, and you would like to test the kangkong from your local grocery store. How could you modify this protocol to extract DNA from the kangkong (to identify the species) and check for presence or absence of E. coli.? Keep in mind that (i) E. coli is free-living and not an endosymbiont, and (ii) plant cells are encased in both a cell membrane and cell wall.arrow_forwardBioinformatics includes all of the following except (A) using computer programs to align DNA sequences. (B) using DNA technology to combine DNA from two different sources in a test tube. (C) developing computer-based tools for genome analysis. (D) using mathematical tools to make sense of biological systems.arrow_forwardPlease answer all of these questions in details Answer all of the following questions a) Define the following terms: biotechnology, Plasmid,Genetic engineering and Transformation b) List two types of medical products that can be produced using DNA tech- nology c) Relate bioethics to the continued development of genetic engineering techniques. d) Describe two major goals of the Human Genome Project. e) Distinguish between proteomics and genomics. f) Outline the different applications of biotechnology g) List some techniques of genetic engineering. h) Delineate the transgenic organisms and their significance. i) Explain the procedure for the following PCR, Gel electrophpresis and Gene therapy j) Describe human genome project and its main goals. k) Discuss the drastic environmental impacts of oil spills and how the mi- crobes like bacteria can help mitigate the problem. l) Give an account of significance of transgenic organisms in food industry. m) Describe the uses of DNA finger…arrow_forward
- Remember that although there are many interesting ideas about genetic engineering of plants and animals, this is specifically about GE bacteria. Please be sure you are answering the following questions: 1) What is the species that was modified, and what species did the introduced genes come from? 2) What is the purpose of the genetic engineering? What were people hoping to accomplish? 3) What are the benefits (or potential benefits) of the engineered bacterium? 4) What are the risks (or potential risks) of the engineered bacterium?arrow_forwardHigh-throughput DNA sequencing technology ... 1.) is far cheaper than Sanger sequencing on a per-basta basis. 2.)can generate millions or billions of base pairs of sequence data for each sample. 3.)often involves shotgun sequencing, in which random fragments of DNA from a sample (rather than a specific, targeted portion of the genome) are sequenced. 4.) All of the abovearrow_forwardIf you were to sequence a human genome today, how would the sequencing differ from that done during the Human Genome Project? Choose only the best answer. You would still use Sanger sequencing. You would still assemble the sequencing reads into a genome using bioinformatics. You still need to clone the DNA fragments prior to sequencing them. All three of the other statements are true.arrow_forward
- DNA technology has many medical applications. Which of the following is not done routinely at present? (A) production of hormones for treating diabetes and dwarfism (B) analysis of gene expression for more informed cancer treatments (C) gene editing by the CRISPR-Cas9 system in viable human embryos to correct genetic diseases (D) prenatal identification of genetic disease allelesarrow_forwardThe idea behind PCR-based diagnostics is that a very small number of microbial genomes in a patient sample can be multiplied by PCR and more easily detected by the clinical team managing the patient’s care. Also, genetic-based diagnostics are very useful for viral infections because we don’t have biochemical tests, etc. to distinguish one virus from another (remember, viruses are metabolically inactive). However, a lot of work goes into the development of these tests. For instance, PCR requires primers that are complementary to the viral genome that is being copied. If primers are complementary to the target genome, what must scientists know to design primers that bind to the viral genome to be copied? (I mean this to be a general question; don’t look up the details of designing primers)arrow_forwardWhole-exome sequencing (WES) is helping physicians diagnose a genetic condition that has defied diagnosis by traditional means. The implication here is that exons in the nuclear genome are sequenced in the hopes that, by comparison with the genomes of nonaffected individuals, a diagnosis might be revealed. (a) What are the strengths and weaknesses of this approach? (b) If you were ordering WES for a patient, would you also include an analysis of the patient’s mitochondrial genome?arrow_forward
arrow_back_ios
SEE MORE QUESTIONS
arrow_forward_ios
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)BiologyISBN:9780134580999Author:Elaine N. Marieb, Katja N. HoehnPublisher:PEARSON
Biology 2eBiologyISBN:9781947172517Author:Matthew Douglas, Jung Choi, Mary Ann ClarkPublisher:OpenStax
Anatomy & PhysiologyBiologyISBN:9781259398629Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa StouterPublisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)BiologyISBN:9780815344322Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter WalterPublisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & PhysiologyBiologyISBN:9781260159363Author:Martin, Terry R., Prentice-craver, CynthiaPublisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)BiologyISBN:9781260231700Author:Sylvia S. Mader, Michael WindelspechtPublisher:McGraw Hill Education
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:PEARSON
Biology 2e
Biology
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:OpenStax
Anatomy & Physiology
Biology
ISBN:9781259398629
Author:McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:9780815344322
Author:Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:9781260159363
Author:Martin, Terry R., Prentice-craver, Cynthia
Publisher:McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Biology
ISBN:9781260231700
Author:Sylvia S. Mader, Michael Windelspecht
Publisher:McGraw Hill Education
Genome Annotation, Sequence Conventions and Reading Frames; Author: Loren Launen;https://www.youtube.com/watch?v=MWvYgGyqVys;License: Standard Youtube License