Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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Zeb1 encodes a transcription factor that activates expression of genes that help cells
migrate (move to different parts of the body) during embryogenesis. Zeb1 is not
expressed in most adult tissues, but can undergo a gain of function mutation in some
tumors. Which change is likely to result from a gain of function mutation in Zeb1?
a) sustaining proliferative signalling
b) activating invasion and metastasis
O c) deregulating cellular energetics
O d) resisting cell death
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Transcribed Image Text:Zeb1 encodes a transcription factor that activates expression of genes that help cells migrate (move to different parts of the body) during embryogenesis. Zeb1 is not expressed in most adult tissues, but can undergo a gain of function mutation in some tumors. Which change is likely to result from a gain of function mutation in Zeb1? a) sustaining proliferative signalling b) activating invasion and metastasis O c) deregulating cellular energetics O d) resisting cell death
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