Understand how a cancer cell from a primary benign tumor is able to leave the primary benign tumor and enter the blood stream or lymph (migration), start to adhere and grow in a nearby environment like a blood vessel near an organ (invasion) and enter into a new organ to grow and form a secondary tumor ( extravasation). What proteins would be involved in these steps and what molecular changes in the ECM or basal lamina would need to occur as well as the cancer cell for this process to happen
Understand how a cancer cell from a primary benign tumor is able to leave the primary benign tumor and enter the blood stream or lymph (migration), start to adhere and grow in a nearby environment like a blood vessel near an organ (invasion) and enter into a new organ to grow and form a secondary tumor ( extravasation). What proteins would be involved in these steps and what molecular changes in the ECM or basal lamina would need to occur as well as the cancer cell for this process to happen
Human Biology (MindTap Course List)
11th Edition
ISBN:9781305112100
Author:Cecie Starr, Beverly McMillan
Publisher:Cecie Starr, Beverly McMillan
Chapter22: Genes And Disease: Cancer
Section: Chapter Questions
Problem 1RQ
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Understand how a cancer cell from a primary benign tumor is able to leave the primary
benign tumor and enter the blood stream or lymph (migration), start to adhere and grow in a nearby environment like a blood vessel near an organ (invasion) and enter into a new organ to grow and form a secondary tumor ( extravasation). What proteins would be involved in these steps and what molecular changes in the ECM or basal lamina would need to occur as well as the cancer cell for this process to happen.
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