Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype
states, and observed the frequencies reported in the table below.
a. Calculate D for genes A and B. (D = gAB9ab - gAb9aB)
b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B?
Frequency
Allele A
0.6
Allele a
0.4
Allele B
0.8
Allele b
0.2
Haplotype AB
Haplotype Ab
Haplotype aB
Haplotype ab
0.48
0.12
0.32
0.08
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Transcribed Image Text:You discover two segregating genes (A and B) that affect resistance in a population of snails. You are interested in determining if the two loci are in LD. You analyzed 100 snails for allelic and haplotype states, and observed the frequencies reported in the table below. a. Calculate D for genes A and B. (D = gAB9ab - gAb9aB) b. Is this population in linkage equilibrium or linkage disequilibrium with respect to genes A and B? Frequency Allele A 0.6 Allele a 0.4 Allele B 0.8 Allele b 0.2 Haplotype AB Haplotype Ab Haplotype aB Haplotype ab 0.48 0.12 0.32 0.08
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