Which parameters are important to include when designing a GWAS (genome-wide association study) to identify genes involved in Polycystic Kidney disease in individuals of Korean ancestry? Select all that apply. Group of answer choices a. Compare Korean individuals with the disease to unaffected Korean individuals b. Pursue SNPs only in exonic loci for further study c. Pursue SNPS only in genes related to kidney development for further study d. Set strong statistical thresholds to identify SNPs related to the disease state over the general variation observed in populations e. Compare Korean individuals with the disease to every available genome for a stronger statistical power.
Which parameters are important to include when designing a GWAS (genome-wide association study) to identify genes involved in Polycystic Kidney disease in individuals of Korean ancestry? Select all that apply. Group of answer choices a. Compare Korean individuals with the disease to unaffected Korean individuals b. Pursue SNPs only in exonic loci for further study c. Pursue SNPS only in genes related to kidney development for further study d. Set strong statistical thresholds to identify SNPs related to the disease state over the general variation observed in populations e. Compare Korean individuals with the disease to every available genome for a stronger statistical power.
Concepts of Biology
1st Edition
ISBN:9781938168116
Author:Samantha Fowler, Rebecca Roush, James Wise
Publisher:Samantha Fowler, Rebecca Roush, James Wise
Chapter10: Biotechnology
Section: Chapter Questions
Problem 13CTQ: Identify a possible advantage and a possible disadvantage of a genetic test that would identify...
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Which parameters are important to include when designing a GWAS (genome-wide association study) to identify genes involved in Polycystic Kidney disease in individuals of Korean ancestry? Select all that apply.
Group of answer choices
a. Compare Korean individuals with the disease to unaffected Korean individuals
b. Pursue SNPs only in exonic loci for further study
c. Pursue SNPS only in genes related to kidney development for further study
d. Set strong statistical thresholds to identify SNPs related to the disease state over the general variation observed in populations
e. Compare Korean individuals with the disease to every available genome for a stronger statistical power.
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