An autosomal locus has alleles A and a. We are given the frequency of individuals with the autosomal recessive phenotype. Which of the following statements is TRUE? Choose all that are true. Note: HWE = Hardy-Weinberg equilibrium a) If we assume HWE, we can calculate both allele frequencies b) If we assume HWE, we can calculate the genotype frequencies that we weren't given c) We can calculate both allele frequencies even if we don't assume HWE d) We can calculate q = Freq(a) even if we don't assume HWE e) Even if we don't assume HWE, we can calculate the genotype frequencies that we weren't given

An autosomal locus has alleles A and a. We are given the frequency of individuals with the autosomal recessive phenotype. Which of the following statements is TRUE? Choose all that are true. Note: HWE = Hardy-Weinberg equilibrium a) If we assume HWE, we can calculate both allele frequencies b) If we assume HWE, we can calculate the genotype frequencies that we weren't given c) We can calculate both allele frequencies even if we don't assume HWE d) We can calculate q = Freq(a) even if we don't assume HWE e) Even if we don't assume HWE, we can calculate the genotype frequencies that we weren't given

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter19: Population Genetics And Human Evolution

Section: Chapter Questions

Problem 9QP: Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic...

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Suppose there is an autosomal locus of 2 alleles, A1 and A2, with probabilities (frequencies) p1 and p2, and the genotype probabilities (frequencies) are P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2, respectively. Prove the Hardy-Weinberg Law, i.e., after one generation of random mating, the genotype probabilities (frequencies) in the offspring are also P(A1A1) = p1*p1, P(A1A2) = 2*p1*p2, and P(A2A2) = p2*p2. Hint: List all possible combinations of random mating. Then list the probabilities of the resulting genotype probabilities (frequencies) in the offspring. Combine the probabilities of random mating and resulting genotype probabilities (frequencies) in the offspring.
Consider a Hardy-Weinburg Equilibrium population with an autosomal locus of 2 alleles, A1 and A2. If P(A1A2) = 8 * P(A1A1), what are the allele frequencies at the locus?
Allele B is a deleterious autosomal dominant. The frequency of affected individuals is 4.0 × 10−6. The reproductive capacity of these individuals is about 30 percentthat of normal individuals. Estimate μ, the rate at whichb mutates to its deleterious allele B. Assume that the frequencies of the alleles are at their equilibrium values.
Cystic fibrosis (CF) is a recessive autosomal disorder. In certainpopulations of Northern European descent, the number of peopleborn with this disorder is about 1 in 2500. Assuming Hardy-Weinberg equilibrium for this trait:A. What are the frequencies for the common (non-disease-causing)allele and the mutant (disease-causing) allele.B. What are the genotype frequencies of homozygous unaffected,heterozygous, and homozygous affected individuals?C. Assuming random mating, what is the probability that twophenotypically unaffected heterozygous carriers will chooseeach other as mates?
While studying the frequency of sickle-cell disease ("sickle cell anemia") in a population living in sub-Saharan Africa, you obtain the following data from a sample of n= 100 people (note that I chose a simpler system for identifying the alleles rather than using "Hb S" for sickle cell allele), which is the actual name and what you used in lab). What is the frequency of the sickle cell allele (b) in the sample below from a human population? Sample Data BB-60 individuals (No sickle cell disease) Bb-30 individuals (No sickle cell disease) bb-10 individuals (Sickle cell disease) 1. 0.25 2. 0.10 3. 0.35 4. 0.60 5. 0.20
This lab exercise requires that we count certain Mendelian traits among students present in the lab. Your professor will explain each trait being addressed and will then ask students to identify if they are dominant or recessive for that specific trait. The collected traits will then be plugged into the Hardy-Weinberg Equilibrium formula in order to calculate frequency of Homozygous dominant, Heterozygous and Homozygous recessive individuals in the same. p2 + 2pq + q2 = 100 given data: trait: hair swirl 19 individuals total. 10 had the homozygous dominant hair swirl trait: clockwise the nine other were recessive please do a step by step explanation with the calculation using this data, as I am very unfamiliar with what values mean what and the equation itself thank you!
Using the HardyWeinberg Law in Human Genetics Suppose you are monitoring the allelic and genotypic frequencies of the MN blood group locus (see Question 2 for a description of the MN blood group) in a small human population. You find that for 1-year-old children, the genotypic frequencies are MM = 0.25, MN = 0.5, and NN = 0.25, whereas the genotypic frequencies for adults are MM = 0.3, MN = 0.4, and NN = 0.3. a. Compute the M and N allele frequencies for 1-year-olds and adults. b. Are the allele frequencies in equilibrium in this population? c. Are the genotypic frequencies in equilibrium?
In a population of 200 people, an allele F has a frequency of 84%. What is the frequency of allele f? Using the Hardy-Weinberg equation, estimate the numbers of homozygous dominant, heterozygous, and homozygous recessive genotypes. (Remember that the formula is: p2 + 2pq + q2 = 1, where p represents the dominant allele and q represents the recessive allele.) *Be sure to account for all 200 people in the population.
Butterflies show 3 phenotypes due to incomplete dominance at the D locus with alleles DY and DB giving green phenotype in heterozygotes and yellow and blue in homozygotes b) In another population only 1% of the butterflies are blue, What is the DY allele frequency?
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Cystic fibrosis (CF) is a recessive autosomal disorder. In certain populations of Northern European descent, the number of people born with this disorder is about 1 in 2500. Assuming Hardy- Weinberg equilibrium for this trait: A. What are the frequencies for the normal and CF alleles? B. What are the genotype frequencies of homozygous normal, heterozygous, and homozygous affected individuals? C. Assuming random mating, what is the probability that two phenotypically unaffected heterozygous carriers will choose each other as mates?
Tay–Sachs disease is an autosomal recessive disorder. Among Ashkenazi Jews, the frequency of Tay–Sachs disease is 1 in 3600. Assuming the Ashkenazi population is in Hardy-Weinberg equilibrium, what proportion of the population is expected to be carriers (e.g. heterozygous) for the Tay–Sachs allele?