Why does epinephrine bind its receptor in a different location than cortisol binds its receptor?     A. The receptor binding site of epinephrine must be extracellular because the cell’s membrane is a barrier that prevents epinephrine from reaching any intracellular binding sites.   B. The membrane blocks cortisol from entering the cell, therefore cortisol must bind the receptor on the cell’s extracellular surface.   C. Cortisol easily passes through the cell’s plasma membrane. Therefore,

A.

The receptor binding site of epinephrine must be extracellular because the cell’s membrane is a barrier that prevents epinephrine from reaching any intracellular binding sites.

B.

The membrane blocks cortisol from entering the cell, therefore cortisol must bind the receptor on the cell’s extracellular surface.

C.

Cortisol easily passes through the cell’s plasma membrane. Therefore, the cortisol receptor is found intracellularly.

D.

Epinephrine can dissolve across the plasma membrane and bind its intracellular receptor.

E.

Both A&C

F.

Both B&D