What is a quantitative trait locus (QTL)? a. A portion of the genome that is a particular quantitative length b. A portion of the genome in which polymorphic markers correlate with a phenotype c. A region of the genome where qualitative traits associate with discrete phenotypes d. A region of the genome that does not follow Mendelian inheritance patterns

What is a quantitative trait locus (QTL)? a. A portion of the genome that is a particular quantitative length b. A portion of the genome in which polymorphic markers correlate with a phenotype c. A region of the genome where qualitative traits associate with discrete phenotypes d. A region of the genome that does not follow Mendelian inheritance patterns

Human Heredity: Principles and Issues (MindTap Course List)

11th Edition

ISBN:9781305251052

Author:Michael Cummings

Publisher:Michael Cummings

Chapter4: Pedigree Analysis In Human Genetics

Section: Chapter Questions

Problem 1CS: Pedigree analysis is a fundamental tool for investigating whether or not a trait is following a...

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Which of the following statements best describe the equation P = G + E + (G X E)?* a. The phenotype is the sum of the genotype and the environment. b. The phenotype of an organism is determined by its genetic traits. c. The phenotype is the total characteristics displayed by an organism that results from the expression of the genes as well as the influence of environmental factors. d. The phenotype is the observable and measurable characteristics of an organism as a result of the interaction of the genes of the organism, environmental factors, and random variation.
For each of the following genetic topics, indicate whether it focuses on transmission genetics, molecular genetics, or population genetics. a. Analysis of pedigrees to determine the probability of someone inheriting a traitb. Study of people on a small island to determine why a genetic form of asthma is prevalent on the islandc. Effect of nonrandom mating on the distribution of genotypes among a group of animals d. Examination of the nucleotide sequences found at the ends of chromosomese. Mechanisms that ensure a high degree of accuracy in DNA replicationf. Study of how the inheritance of traits encoded by genes on sex chromosomes (sex-linked traits) differs from the inheritance of traits encoded by genes on nonsex chromosomes (autosomal traits)
Which of the following can the results of a QTL tell you? a. Identify all of the causative genes underlying a trait. b. Identify the specific marker locus causes the phenotype you are tracking. c. Identification of regions of the genome that are associated with a trait. d. Identify haplotypes associated with specific traits of interest in other populations.
While traits Mendel worked with all adhered to his principles of inheritance, this is not the norm because phenotypes are typically a combination of both genetic and what other kind of influence? A. nature B. nurture C. environmental D. both nurture and environmental
Which of the following statements about mendelian or complex diseases true?. A Genome- wide association studies rely on polymorphic markers that are linkage disequalibrium with alleles that contribute to the traits of interest. B. Genetic methods for studying Mendelian phenotype such as crossing is not useful for mapping quantitive trait loci. C. Mapping of quantitative trait loci does relies on genetic variations that directly contribute to the trait of interest.
How can a polygenic trait be easily identified? a. There ae only two possible phenotypes for the trait. b. The graphing of the possible phenotypes results in a bell curve. c. The presence of the polygenic trait masks the other possible alleles involved. d. The environment has a greater influence on the trait.
In a hypothetical population, matings involving two individuals heterozygous for the phenylketonuria allele on chromosome 12 result in 10% of the offspring showing the effects of the disease. This percentage arises because: A. the trait has pleiotropic effect B. the trait assorts independently C. the trait has low expressivity D. the trait has only partial penetrance E. the trait is sex-influenced
Please help with the following: How does penetrance differ from expressivity in genetics? A. Penetrance is the percentage of individuals with a specific genotype that exhibit the expected phenotype while expressivity is the degree to which a phenotypic character is expressed. B. Penetrance is the degree of lethality of a specific genotype while expressivity is how frequently that genotype is seen in the population. C. Penetrance is the presence of more than two alleles at a locus within a group of individuals while expressivity is the influence of sex on which alleles express themselves. D. None of the above. E. Penetrance refers to the paternal effects of a gene while expressivity refers to the maternal effects of a gene.
Which of the following is the definition of the term named Genotype? a.Refers to genes that have identical alleles b.Genetic constitution of an organism c.Alternative form of a gene d.Trait expressed in the F1 generation e.Fundamental physical and functional unit of heredity f.Physical expression of traits of an organism
a. What is a complex trait? How many genes do we expect to affect a complex trait? b. How linkage (and linkage disequilibrium) relates to a GWAS?
1. Name two pea plant traits studied by Gregor Mendel. 2. Define genotype. 3. Define phenotype. 4. Why would a pea plant that is heterozygous for plant height have the dominant phenotype? 5. A pea plant with the recessive phenotype for plant height would have which of the following genotypes? 1. TT 2. tt 3. Tt 4. TT or Tt 6. What is the difference between a Mendelian trait and a polygenic trait? 7. Why are females more likely to be carriers for color blindness than to be color blind themselves? 8. Which of the following is a polygenic trait in humans? 1. Hitchhiker's thumb 2. Earlobe attachment 3 Skin color
Match the pattern of inheritance to the appropriate term. A. Heterozygotes with different alleles of the DTL1 gene survive better than homozygotes B. The disease is usually passed from a mother to all children C. Pure-breeding pumpkin plants grown on sandy soil have bigger seeds than plants of the same pure-breeding lineage grown on peaty soil. D. A cross between a true-breeding plant with serrated leaf edges and a true- breeding plant with smooth leaf edges produces an F1 generation with 88% plants with serrated leaves. E. A cross between two heterozygotes, DdFf, produces offspring in three phenotypic groups; Long wings in offspring with genotype D_F_, short wings in offspring with D_ff, and no wings in offspring with the genotypes ddF_ and ddff. F. Individuals homozygous for a mutation in SME have a heightened sense of smell and large earlobes. G. Grey chickens bred together have offspring that are black, grey and white in a 1:2:1 ratio H.Alleles at locus S…

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	a.	A portion of the genome that is a particular quantitative length
	b.	A portion of the genome in which polymorphic markers correlate with a phenotype
	c.	A region of the genome where qualitative traits associate with discrete phenotypes
	d.	A region of the genome that does not follow Mendelian inheritance patterns