Which of the following statements regarding CD1 is correct? a. CD1 binding grooves are very similar to those of MHC class I molecules. b. Lipid antigens of CD1 bind with high affinity and are rarely exchanged. c. CD1 comprises three MHC class I-like heavy chains known as CD1c, CD1d, and CD1e, each belonging to a different functional group. d. CD1 molecules form heterodimers with β2-microglobulin. e. When a CD1d molecule presents sulfatide to a γ:δ T cell, all three CDR loops of both the γ and δ chains must be engaged to activate the T cell. f. CD1 genes are located in the HLA complex on chromosome 6.
Which of the following statements regarding CD1 is correct? a. CD1 binding grooves are very similar to those of MHC class I molecules. b. Lipid antigens of CD1 bind with high affinity and are rarely exchanged. c. CD1 comprises three MHC class I-like heavy chains known as CD1c, CD1d, and CD1e, each belonging to a different functional group. d. CD1 molecules form heterodimers with β2-microglobulin. e. When a CD1d molecule presents sulfatide to a γ:δ T cell, all three CDR loops of both the γ and δ chains must be engaged to activate the T cell. f. CD1 genes are located in the HLA complex on chromosome 6.
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
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| Which of the following statements regarding CD1 is correct? |
| a. CD1 binding grooves are very similar to those of MHC class I molecules. |
| b. Lipid antigens of CD1 bind with high affinity and are rarely exchanged. |
| c. CD1 comprises three MHC class I-like heavy chains known as CD1c, CD1d, and CD1e, each belonging to a different |
| d. CD1 molecules form heterodimers with β2-microglobulin. |
| e. When a CD1d molecule presents sulfatide to a γ:δ T cell, all three CDR loops of both the γ and δ chains must be engaged to activate the T cell. |
| f. CD1 genes are located in the HLA complex on chromosome 6. |
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