Which of the following statements correctly describe the peptide bond hydrolysis reaction? [Select all that apply.] At high pH the effectiveness of the nucleophile improves. The reaction is faster at pH 14.0 than at pH 7.0. The reaction is fastest at pH 7.0. At high pH the effectiveness of the electrophile improves. The reaction is faster at pH 0.0 than at pH 7.0.

Chemistry for Today: General, Organic, and Biochemistry
9th Edition
ISBN:9781305960060
Author:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Chapter15: Carboxylic Acids And Esters
Section: Chapter Questions
Problem 15.64E
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Which of the following statements correctly describe the peptide bond hydrolysis reaction?
[Select all that apply.]
At high pH the effectiveness of the nucleophile improves.
The reaction is faster at pH 14.0 than at pH 7.0.
The reaction is fastest at pH 7.0.
At high pH the effectiveness of the electrophile improves.
The reaction is faster at pH 0.0 than at pH 7.0.
Transcribed Image Text:U Which of the following statements correctly describe the peptide bond hydrolysis reaction? [Select all that apply.] At high pH the effectiveness of the nucleophile improves. The reaction is faster at pH 14.0 than at pH 7.0. The reaction is fastest at pH 7.0. At high pH the effectiveness of the electrophile improves. The reaction is faster at pH 0.0 than at pH 7.0.
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