Which of the following mutations would likely have the greatest negative impact on the protein product of a gene? Group of answer choices a single base deletion close to the end of the coding region of a gene a single base insertion just after the start of the coding region of the gene a deletion of three bases near the middle of the gene a base-pair substitution

What is the minimal number of insertions/deletions of nucleotides that would result in a frameshift mutation?

G-LO37 Identify the consequences of mutations in different regions of a gene. The image below represents two strands of DNA: the top one corresponds to a healthy individual, and the bottom one of a sibling potentially affected with a disease due to genetic mutations Mutation 1 A + с AUA ACA AUG Met ACG GUU GUC GUA GUG Val GCU GCC GCA GCG It will result in mRNA produced Mutation 2 It will result in no mRNA produced 500 AGG The protein produced will be normal 500 + GGG Ala The Select all that applies about Mutation 1 (position -6): AAGLys AGA Arg GGU GGC GGA GGG GAC Asp GAA Glu GAGJ Gly The protein produced will have a different amino acid 1235 ATT 1235 TTT 070 2070 ALL The mutation occurs in the promoter region, and this means that the mRNA cannot be produced 1535 The mRNA and protein will both be normal because the mutation occurs outside of the consensus region of the promoter G 1535 с Affected

Mutations can be caused by which process?   faulty DNA repair   nondisjunction   base sequence deletion   All of the above