Which of the following is/are a transition mutation(s)? (select any that apply) A to T   A to G   C to G   A to C   C to A

Which of the following would be most likely to be a conservative or mild mutation? Histidine (His) > Valine (Val) Arginine (Arg) > Aspartate (Asp) Valine (Val) > Isoleucine (Ile) Leucine (Leu) > Lysine (Lys) Glutamate (Glu) > Proline (Pro)

What three different types of mutations involve changes in a single base, and what effect can each of them have on a coding sequence? Which type is the most common? Which type has the most severe effect on the function of the encoded protein?

What type of mutation is shown below: CGG GGG GAG TCT TTT TAT GCA GCT changes to: CGG GGG GAG CTT TTTATG CAG CT A frame shift mutatuion which resulted from a deletion. O Point mutation in which one nucleotide was changed. O Point mutation in which a length of nucleotides were changed. O A frame shift mutatuion which resulted from an insertion.

Please help me, this is from practice, double check your answers, previous tutors got it wrong

Consider this sequence below:  GAG TAC ACG AGT GGA Which of the following options is an example of a non-synonymous point mutation? (remember to translate to mRNA!) A. GAG TAC AAT CGA GTG GA B. GAG TAC ACG GGT GGA C. GAG TAC A–G AGT GGA D. GAG TAC ACG AGA GGA

Which of the following mutations is likely to cause the most dramatic mutant effects: Missense, nonsense, sense? Explain your answer.

An individual with the genetic condition cystic fibrosis has CFTR protein with the amino acid histidine (at position 482), where the normal CFTR protein has arginine. No other changes are observed in the protein. This is the result of a ____ mutation. Select one: a. nonsense b. frameshift c. silent d. missense

G T-A what's called a FRAMESHIFT mutation, meaning the reading "frame" čhanging the amino acid sequence from this point forward G-Cc A-u SUBSTITUTION (one base is substituted for another) --- If a substitution changes the amino acid, it's called a MISSENSE mutation --- If a substitution does not change the amino acid, it's called a SILENT mutation --- If a substitution changes the amino acid to a "stop." it's called a NONSENSE mutation Complete the boxes below. Classify each as Deletion, Insertion or Substitution AND as either frameshift, missense, silent or nonsense (Hint: Deletion & Insertion will always be frameshif Original DNA Sequence: TACA C C T T G G C G A CGAC T ... MRNA Sequence: Au GduGilAAdk GcuadiGA stait -TrP Pen-frg-cys stop Amino Acid Sequence: Mutated DNA Sequence #1 TA C»A(T C•T T G•G C GªA C G' A C T.. What's the mRNA sequence? AUGOUTAGOAAC•CECOUGIC•UEIA amino acid sequence? Will there likely be effects? yes (Circle th metootop What type of mutation is this? NONSense…

When considering the mutational options for a nucleotide such as thymine, there is a single transition and two transversion type mutations that are possible, which is why we observe transversions to occur more frequently in nature when genomes are examined. O True O False