When glycolytic flux exceeds the mitochondrial flux, the majority of pyruvate is converted to     pyruvate     glucose-1-phosphate     lactate     acetyl-CoA

Which of the following glycolytic enzymes must consume ATP during phosphorylation of its preferred substrate molecule? phosphoglycerate mutase pyruvate kinase succinate dehydrogenase hexokinase phosphoglycerate kinase

When pyruvate dehydrogenase complex is phosphorylated, it is (active or inactive)

Which of the following conditions is most likely to force a muscle cell to metabolize glucose anaerobically(fermentation) under normal oxygenation ? - Glyceraldehyde-3-phosphate dehydrogenase deficiency - Lactate dehydrogenase deficiency  -Pyruvate kinase deficiency  -Aldolase deficiency  - Cytososic Glycerol-3-phosphate dehydrogenase deficiency

In the liver, what is the fate of pyruvate under conditions of the Cori Cycle? Acetyl CoA to fuel TCA Conversion to oxaloacetate primarily for glucose biosynthesis Conversion to lactate Conversion to oxaloacetate primarily for amino acid biosynthesis

The first step of gluconeogenesis involves the carboxylation of pyruvate and has a large negative delta G (i.e very exergonic). Explain how it is possible that this step can be exergonic if we know that adding CO2 onto molecules is fundamentally a destabilizing phenomenon?

What enzyme will not be used if the oxidative portion of the pentose phosphate pathway is operating to produce ribose 5-phosphate? Ribulose 5-phosphate isomerase 6-phosphoglucono-lactonase 6-phosphogluconate dehydrogenase Transaldolase

Does Pyruvate Dehydrogenase Complex have coenzymes and Allosteric regulation?