Which of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the above

Which of the following reactions required dihydrolipoyl dehydrogenase? Oxidative decarboxylation of pyruvate Oxidative decarboxylation of a-ketoglutarate Both A and B Neither A nor B Fatty acid biosynthesis is stimulated by: Decreased levels of citrate Increased levels of palmitoyl-CoA Increased levels epinephrine Increased levels of AMP All of the above None of the above

Biochemistry

6th Edition

ISBN:9781305577206

Author:Reginald H. Garrett, Charles M. Grisham

Publisher:Reginald H. Garrett, Charles M. Grisham

Chapter19: The Tricarboxylic Acid Cycle

Section: Chapter Questions

Problem 22P: Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is...

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Study Figure 19.18 and decide which of the following statements is false. Pyruvate dehydrogenase is inhibited byÂ· NIADH. Pyruvate dehydrogenase is inhibited by AÎ¤Î¡. Citrate synthase is inhibited by NADH. Succinyl-CoA activates citrate synthase. Acetyl-CoA activates pyruvate carboxylase.
Which of the following is NOT part of the multi-enzyme complex of fatty acid synthase? O enoyl-ACP reductase O acetyl CoA carboxylase O 3-hydroxybutyrylACP-dehydratese O B-ketoacyl-ACP reductase
What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
Which enzyme is used for both the synthesis and breakdown of acetoacetate? thiolase O HMG-CoA synthase OB-hydroxybutyrate dehydrogenase O B-Ketoacyl-CoA transferase
What is(are) the only active site(s) not used in the second round of fatty acid synthase? Select all that apply. Group of answer choices Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
What is the final reaction in the final round of fatty acid synthase? Acetyl-CoA ACP Transacylase Beta-Ketoacyl- ACP Synthase Beta-Ketoacyl- ACP Dehydrase Palmitoyl thioesterase Malonyl-CoA ACP Transacylase Enoyl-ACP Reductase
Which of these are components of animal fatty acid synthase (FAS)? ✔B-ketoacyl reductase enoyl reductase acetyl transacylase acyl CoA synthetase 3-hydroxyacyl dehydratase acyl CoA dehydrogenase Incorrect Fatty Acid Synthase (this diagram based on fungal FAS)
If Vitamin B1 is deficient, which of the following intermediates is/are likely to accumulate inmitochondria? Pyruvate a-ketoglutarate Both A and B Neither A nor B Malonyl-CoA synthesized by the action of acetyl-CoA carboxylase II is primarily used: To synthesize fatty acids To inhibit fatty acid oxidation Both A and B Neither A nor B
Glucagon secretion inhibits intracellular acetyl-CoA carboxylase activity through a number of different methods. Make a list of everything that comes to mind.
Fatty acids are activated for breakdown through the action of acyl-CoA synthestase. Which of the following statements regarding acyl-CoA synthetase is not true? ● It catalyzes the addition of CoA to the fatty acid One of the products of the reaction is ADP. O The free energy change for the reaction catalyzed by this reaction is close to 0 kJ/mol, but the subsequent hydrolysis of pyrophosphate drives the reaction forward. O The reaction results in the formation of a thioester bond.
Fatty acid biosynthesis begins with the condensation of a two-carbon acetyl residue from acetyl-COA and oxaloacetate, while oxidation leads to the release of two carbon units, acetyl-CoA and fatty acyl-CoA. However, these two processes are not simple reversal. Compare and contrast these two pathways.
Discuss the regulation of fatty acid metabolism by the isozymic forms of acetyl CoA carboxylase. Explain the reciprocal control of fatty acid synthesis and degradation and the various means by which this control is achieved