What is the difference between a proto-oncogene and a tumor suppressor gene?  How can mutations in these genes lead to cancer

Why do mutations in genes that encode DNA-repair enzymes often produce a predisposition to cancer?

In cell growth, how does the normal allele of BRCA1 work? Is it an oncogene or a tumor suppressor gene?

Explain Mutations in tumor-suppressor genes are recessive at the cellular level but dominant at the organismal level.

What is the difference between benign and malignant tumors? What is the disadvantage of this classification?

How tumor-suppressor genes contribute to cancer whenmutated or abnormally expressed ?

Researchers have identified some tumors that have no recurrent mutations or deletions in known oncogenes or tumor-suppressor genes and no detectable epigenetic alterations. However, these tumors often have large chromosomal deletions. What are some possible explanations that could account for the genetic causes behind these tumors?

how can mutations in several genes drive cancer?

There are three broad categories of cancer-related genes: proto-oncogenes, tumor suppressor genes, and DNA stability/repair genes. Define each of these categories and indicate which one you think the RB1 gene belongs to and why.

how are the hallmarks resisting cell death and enabling replicative immortality essential for cancer development. explain each in 3-5 sentences.