This data shows the efficacy of different treatments on the survival rates of patients with glioblastomas, as well as methylated, and on methylated MGMT promoters. A. Explain the trends in the figure B. Relate MGMT methylation to the central dogma/flow of genetic information, and how genes are expressed. 

An Illustrated Guide To Vet Med Term
4th Edition
ISBN:9781305465763
Author:ROMICH
Publisher:ROMICH
Chapter15: Feed And Protect Me
Section: Chapter Questions
Problem 1CP
icon
Related questions
Question
This data shows the efficacy of different treatments on the survival rates of patients with glioblastomas, as well as methylated, and on methylated MGMT promoters. A. Explain the trends in the figure B. Relate MGMT methylation to the central dogma/flow of genetic information, and how genes are expressed. 
-
Unmethylated,
radiotherapy
Unmethylated,
radiotherapy plus
temozolomide
Methylated,
radiotherapy
Methylated,
radiotherapy plus
temozolomide
Probability of Overall Survival (%)
100-
90-
80-
70-
60-
50-
40-
30-
20-
10-
0-
0
6
12
18
001 A
P=0.007
P=0.06
4
24
soll un
Months
30
36
7
42
I
Figure 2. Treatment of Glioblastoma as Related to Overall Survival. From The New England Journal of Medicine, Hegi, M.E. et al.,
MGMT gene silencing and benefit from temozolomide in glioblastoma, 352, 997-1003, Figure 3A. Copyright © 2005 Massachusetts
Medical Society. Reprinted with permission from Massachusetts Medical Society.
Transcribed Image Text:- Unmethylated, radiotherapy Unmethylated, radiotherapy plus temozolomide Methylated, radiotherapy Methylated, radiotherapy plus temozolomide Probability of Overall Survival (%) 100- 90- 80- 70- 60- 50- 40- 30- 20- 10- 0- 0 6 12 18 001 A P=0.007 P=0.06 4 24 soll un Months 30 36 7 42 I Figure 2. Treatment of Glioblastoma as Related to Overall Survival. From The New England Journal of Medicine, Hegi, M.E. et al., MGMT gene silencing and benefit from temozolomide in glioblastoma, 352, 997-1003, Figure 3A. Copyright © 2005 Massachusetts Medical Society. Reprinted with permission from Massachusetts Medical Society.
Expert Solution
steps

Step by step

Solved in 4 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
An Illustrated Guide To Vet Med Term
An Illustrated Guide To Vet Med Term
Biology
ISBN:
9781305465763
Author:
ROMICH
Publisher:
Cengage
3-2-1 Code It
3-2-1 Code It
Biology
ISBN:
9781337660549
Author:
GREEN
Publisher:
Cengage
Curren'S Math For Meds: Dosages & Sol
Curren'S Math For Meds: Dosages & Sol
Nursing
ISBN:
9781305143531
Author:
CURREN
Publisher:
Cengage
Understanding Health Insurance: A Guide to Billin…
Understanding Health Insurance: A Guide to Billin…
Health & Nutrition
ISBN:
9781337679480
Author:
GREEN
Publisher:
Cengage
Nutrition Now
Nutrition Now
Health & Nutrition
ISBN:
9781337415408
Author:
Brown
Publisher:
Cengage
Basic Clinical Laboratory Techniques 6E
Basic Clinical Laboratory Techniques 6E
Biology
ISBN:
9781133893943
Author:
ESTRIDGE
Publisher:
Cengage