The U1 splice donor site is critical for positioning of the U1snRNP for appropriate splicing. What site/region(s) participates directly in the phosphoester bond exchange that forms the lariat leading to the correct excision of the intronic segment? Options:   the branch point adenosine   the poly A stretch within the intron (high conservation ~80%)   U2AF binding site (GU) at the 3' intron/exon junction   a and b only   a, b and c

Human Heredity: Principles and Issues (MindTap Course List)
11th Edition
ISBN:9781305251052
Author:Michael Cummings
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Chapter15: Genomes And Genomics
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Problem 13QP
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The U1 splice donor site is critical for positioning of the U1snRNP for appropriate splicing. What site/region(s) participates directly in the phosphoester bond exchange that forms the lariat leading to the correct excision of the intronic segment?

Options:
 

the branch point adenosine

 

the poly A stretch within the intron (high conservation ~80%)

 

U2AF binding site (GU) at the 3' intron/exon junction

 

a and b only

 

a, b and c

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