The thiolate anion of CoA acts as a/an nucleophile attacking the carbonyl carbon of the enzyme bound intermediate, displacing AMP and forming a fatty acyl CoA.

Q: Fatty acid biosynthesis begins with the condensation of a two-carbon acetyl residue from acetyl-COA…

A: Fatty acid biosynthesis is the creation of fatty acids from acetyl-CoA and NADPH through the action…

Q: Acetyl-CoA + HCO3- → Malonyl-CoA However, the ΔG of this reaction is much greater than zero. In…

A: The formation of malonyl-CoA from acetyl-CoA is an irreversible three-step process, catalyzed by…

Q: Most fatty acids have an even number of carbons and, therefore, are completely metabolized to…

A: For the given reaction the co enzymes required are given below: There are two steps reaction

Q: Explain why people with Medium-chain acyl-CoA dehydrogenase deficiency are advised to eat a diet…

A: People with Medium-chain acyl-CoA dehydrogenase (MCAD) deficiency are advised to eat a diet rich in…

Q: 3-Hydroxy-3-methylglutaryl CoA is on the pathway for cholesterol biosynthesis. It is also a…

A: Cholesterol is a lipid molecule containing four hydrocarbon rings linked with each other, along with…

Q: What kind of inhibitor is threo-sphingosine? Explain this type of inhibition.

A: Introduction:  Enzymes are the catalyst of life. Enzyme inhibitor is defined as a substance which…

Q: Explain the chemical change that occurs in converting kynurenine (a product of tryptophan…

A: Kynurenine is a metabolite of the amino acid tryptophan and used in the production of niacin.…

Q: Which of the following is most helpful in ensuring that wasteful (unproductive) hydrolysis of acetyl…

A: " Since you're posted multiple questions I will provide the solution  of only firstquestion you ask…

Q: Draw the structure of the acyl CoA formed from palmitic acid, C 15H 31CO 2H. Use this acyl CoA to…

A: Fatty acids are catabolised by β-oxidation. Fatty acid reacts with coenzyme A and forms an acyl CoA.…

Q: Only one acetyl CoA molecule is used directly in fatty acid synthesis. Identify the carbon atoms in…

A: Fatty acids are the biomolecules that are formed of a long hydrocarbon chain attached to the…

Q: TAG

A: The breakdown of one biomolecule to complete oxidation to its molecular level is called oxidation.…

Q: Although both acetyl-CoA and succinyl-CoA are high-energy thioesters, their chemical energy is used…

A: A tricarboxylic acid (TCA) cycle, commonly known as the Krebs or citric acid cycle, is the primary…

Q: The enzyme chymotrypsin, catalyses the hydrolysis of nitrophenyl acetate and pther acyl esters. Name…

A: Chymotrypsin is a digestive enzyme belonging to a super family of enzymes called serine proteases.…

Q: Mercuric ion and methanol are inhibitors of alcohol dehydrogenase. Explain.

A: Alcohol (ADH) dehydrogenase is an enzyme that helps in the interconversion of alcohol into ketones…

Q: Incubation of the norsolinic acid synthase holo-ACP with malonyl CoA gave malonyl-S-ACP (molecular…

A: Enzymes are biological catalysts that catalyse biochemical reactions. Most enzymes are made up of…

Q: Arrange the intermediates of galactose metabolism via gycolysis in order trom the first intermedate…

A: Galactose is a monosaccharide having same chemical formula as glucose. It is a C-4 epimer of…

Q: Isoleucine is degraded to acetyl CoA and succinyl CoA. Suggest a plausible reaction sequence, based…

A: The degradation of branch chain amino acids is catalyzed by an aminotransferase which was present in…

Q: Compare and contrast Pyruvate Dehydrogenase with a-ketoglutarate dehydrogenase Outline the…

A: Enzymes are essential for the functioning of living cells and play a crucial role in maintaining…

Q: Consider a preparation that contains all the enzymes and cofactors necessary for fatty acid…

A: Questions 1 - This process takes place in the cytoplasm of the cell. Most of the acetyl-CoA which is…

Q: Look at the synthesis of citryl CoA by citrate synthase in the figure.  Which of the 4 general…

A: Citrate synthase is an important enzyme in citric acid cycle that catalyses the conversion of oxalo…

Q: In order to provide the acetyl-CoA molecules to produce 3 equivalents of palmitic acid, how many…

A: Glucose is generally a monosaccharide that has six carbon atoms and an aldehyde group and it is…

Q: Citrate synthase is regulated by another metabolite that has the opposite effect (i.e., stimulates…

A: The citric acid cycle carries out the complete oxidation of acetyl CoA molecules that are obtained…

Q: What would be the effect on fatty acid synthesis of a mutation in ATPcitrate lyase that reduces the…

A: Biomolecules are organic molecules that occur and function in living systems. Biomolecules consist…

Q: Fatty acid synthesis requires the activation of acetyl CoA to malonyl CoA. However, its condensation…

A: Fatty acids are broken down to acetyl Co-A and the precursor for the fatty acid synthesis is acetyl…

Q: During the process of synthesizing palmitate (C16), an acyl ACP __________. For the sake of this…

A: Fatty acid β-oxidation is the process by which fatty acids are broken down to produce energy.

Q: One    metabolic    scenario that    leads to insulin    resistance is the elevation    of the…

A: Insulin resistance is defined as the inactivity of insulin in its target cells. The examples of…

Q: Beta-Oxidation of a 15:14⁹ fatty acid will result in the production of which of the following? 7…

A: The given fatty acid is composed of 15 carbon and it has a single double bond present in it. It…

Q: A biological Claisen reaction occurs in the conversion of two acetyl CoA molecules to one…

A: Introduction: The condensation reactions involve the formation of new carbon-carbon bonds. The most…

Q: Can an amino acid be both glucogenic and ketogenic? Explain why or why not.

A: The the amino acid is the basic subunit of the protein, which helps to form protein functional…

Q: In the presence of an excess of [14C]acetyl- COA, the metabolic pool of malonyl-CoA becomes labeled…

A: Lipids are the biomolecules that are esters of fatty acids along with alcohol where fatty acids are…

Q: The reaction is reversible. Check all that apply. acetyl CoA lactate ethanol

A: “Since you have asked multiple questions, we will solve the first question for you. If you want any…

Q: The peroxisomal enzyme b-ketoacyl–CoA-thiolase does notbind medium-chain acyl-CoA, in contrast to…

A: The peroxisomal enzyme beta-ketoacyl CoA thiolase does not bind medium chain acyl CoA in contrast to…

Q: Consider the complete oxidation of a mixed TAG containing the following fatty acid residues: At…

A: Background information for Triglycerides or Triacylglycerols (TAG) Triacylglycerols are a group of…