Citrate synthase is regulated by another metabolite that has the opposite effect (i.e., stimulates citrate synthase). Choose the description of a condition where a positive regulator activates citrate synthase. Low [ATP/ADP] ratio. ADP is an allosteric activator of citrate synthase. High [citrate]. Citrate is a positive allosteric activator. High [NADH/NAD*] ratio. NADH is a positive allosteric activator. High [ATP/ADP] ratio. High ATP substrate levels favor product formation.

Biology 2e
2nd Edition
ISBN:9781947172517
Author:Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:Matthew Douglas, Jung Choi, Mary Ann Clark
Chapter7: Cellular Respiration
Section: Chapter Questions
Problem 9RQ: GTP or ATP is produced during the conversion of isocitrate into ketoglutarate succinyl CoA into...
icon
Related questions
Question
100%

In the presence of saturating amounts of oxaloacetate, the activity of citrate synthase from pig heart tissue shows a sigmoid dependence on the concentration of acetyl‑CoA. When succinyl‑CoA is added, the curve shifts to the right and the sigmoid dependence is more pronounced.

Activity (% of Vmax)
100F No
80
60
40
20
I
succinyl-CoA
Succinyl-CoA
added
1
20 40 60 80 100 120
[Acetyl-CoA] (um)
Transcribed Image Text:Activity (% of Vmax) 100F No 80 60 40 20 I succinyl-CoA Succinyl-CoA added 1 20 40 60 80 100 120 [Acetyl-CoA] (um)
Citrate synthase is regulated by another metabolite that has
the opposite effect (i.e., stimulates citrate synthase).
Choose the description of a condition where a positive
regulator activates citrate synthase.
Low [ATP/ADP] ratio. ADP is an allosteric
activator of citrate synthase.
High [citrate]. Citrate is a positive
allosteric activator.
High [NADH/NAD*] ratio. NADH is a positive
allosteric activator.
High [ATP/ADP] ratio. High ATP substrate levels
favor product formation.
Transcribed Image Text:Citrate synthase is regulated by another metabolite that has the opposite effect (i.e., stimulates citrate synthase). Choose the description of a condition where a positive regulator activates citrate synthase. Low [ATP/ADP] ratio. ADP is an allosteric activator of citrate synthase. High [citrate]. Citrate is a positive allosteric activator. High [NADH/NAD*] ratio. NADH is a positive allosteric activator. High [ATP/ADP] ratio. High ATP substrate levels favor product formation.
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 3 steps

Blurred answer
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax