The most commonly used biochemical reducing agent is: a) NADH b) NADPH c) FADH2 d) LiALH4
Hexokinase catalyzes: a) conversion of glucose to glucose-6-phosphate b) conversion of glucose-6-phosphate to fructose-6-phosphate c) conversion of fructose-6-phosphate to fructose-1,6-biphosphate d) cleavage of fructose-1,6-biphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate
Which one of these molecules is not found in glycolysis? a) 1,3-biphosphoglycerate b) phosphoenolpyruvate c) pyruvate d) oxaloacetate
The major regulatory enzyme of glycolysis is: a) hexokinase b) phosphofructokinase c) aldolase d) triose isomerase
NADH is produced at which step in glycolysis? a) conversion of fructose-6-phosphate to fructose-1,6-biphosphate b) cleavage of fructose-1,6-biphosphate to glyceraldehyde-3-phosphate and dihydroxyacetone phosphate c) conversion of glyceraldehyde-3-phosphate to 1,3-biphosphoglycerate d) conversion of phosphoenolpyruvate to pyruvate
The main use of fermentation reactions is: a) to produce extra pyruvate to feed into the Krebs Cycle b) to generate kinetic acid for phospholipid synthesis c) to keep glycolysis going under low oxygen conditions by recycling NAD d) to supply intermediates which are used in
to generate a solution
a solution
- Isozymes: d) One way of regulating metabolic pathways is through isozymes. What is an isozyme? e) Provide a concrete example of an isozyme from carbohydrate metabolism. f) From your chosen isozyme in part b), describe how it is regulated differently in various cells.arrow_forwardWhich of the following statements is INCORRECT? OA) The inhibition of phosphofructokinase leads to the inhibition of hexokinase. B) Fructose-1,6-bisphosphate activates pyruvate kinase. OC) In the liver, phosphofructokinase is activated by citrate. OD) GLUT5 transports fructose.arrow_forwardIn the ubiquitin-proteasome pathway of degradation, what component is most important in determining specificity when selecting proteins for destruction? a)ubiquitin b)E1 ubiquitin-activating enzyme c)E2 ubiquitin-conjugating enzyme d)E3 ubiquitin-protein ligase e)19S proteasomearrow_forward
- 14) Which of the following statements is true under the conditions provided: the enzyme concentration is 0.5 nM, substrate concentration is 10 µM, and the KM = 20 µM? a) The enzymatic reaction occurs at maximal velocity. b) The enzymatic reaction occurs between half-maximal and maximal velocity. c) The enzymatic reaction occurs at around half-maximal velocity. d) The enzymatic reaction occurs at between zero and half-maximal velocity. e) Not enough information given to know about the enzymatic reaction rate.arrow_forwardAn intermediate of the citric acid cycle that undergoes reductive amination with glutamine as nitrogen donor is a-ketoglutarate a) b) Glutamine c) NADPH d) H+arrow_forwardThe peptide bond on the C=O side of bulky hydrophobic residues is cleaved by a) Trypsin b) RNase H c) succinate dehydrogenase d) chymotrypsin e) Factor VIII ( explanation not needed) thank youarrow_forward
- What metabolic substrate is produced from the carbon atoms of each of the following amino acids?Spell out the full name of the compound. 1) isoleucine 2) asparagine 3) threonine 4) argininearrow_forwardDi-isopropyl fluorophosphate is a(n) .................. inhibitor of chymotrypsin ? a) allosteric b) irreversible c) uncompetitive d) competitive e) mixedarrow_forwardVitamin K questionsa) What transformation of glutamate side chains is Vitamin K (as its reduced form, VitaminKH2) involved in, and what is the relevance of this reaction to blood clotting?b) How does the blood thinner Coumadin (warfarin) prevent clotting?c) How can the dietary intake of large amounts of green vegetables, such as broccoli or kaleinterfere with the action of Coumadin?arrow_forward
- Which of the following intermediates of the TCA cycle has 5 carbons? (Hint: You don't need to have memorized specific structures for this question, just recall what molecules the TCA cycle starts with and where in the cycle carbons are lost as CO2 ). a) Fumarate b) None of the above c) Succinyl CoA d) Citrate e) Oxaloacetatearrow_forwardWhich of the following describes a purpose for the function of phosphoglucoisomerase? a) allows for phosphorylation for trapping the molecule in the cell b)promotes substrate level phosphorylation and formation of ATP c) allows formation of a primary alcohol necessary for the next step of phosphorylation d)facilitates epimerization, the change in stereochemistry at one chiral carbonarrow_forwardEnzyme + acetate + CoA ---> enzyme + acetyl _ CoAIn the reaction above, the enzyme is acting as a A) Modulator B) Cofactor C) Catalyst D) Activatorarrow_forward
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