Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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What enzyme is inhibited by the group of medications known as statins?
a)HMG-CoA synthase
b)Aromatase
c)Fatty acid synthase
d)Cyclooxygenase
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- What chemical is the structural basis of the bile salts, Vitamin D, and all of the steroid hormones to include estrogen, progesterone, and testosterone? A) Cholesterol B) Arginine C) Glucose D) Acetyl CoA E) Glucose-6-dehydrogenasearrow_forwardWhich of the following statements is CORRECT? A) Hexokinase IV is allosterically inhibited by glucose-6-phosphate. B) AMP is an allosteric inhibitor of phosphofructokinase-1. C) ATP functions as a chemical inhibitor of pyruvate kinase within muscle. D) Pyruvate kinase is allosterically activated by fructose-1,6-bisphosphate. E) A and D F) C and Darrow_forwardWhich of the following are needed to convert fructose 6-phosphate to fructose 1,6-bisphosphate? a) Phosphofructokinase, ATP, and Mg2+ b) only phosphofructokinase c) Phosphofructokinase, ADP, and Mg2+ d) only phosphofructokinase and Mg2+arrow_forward
- Which of the following is true regarding the reaction catalyzed by the enzyme PEPCK? a) It produces a high energy molecule with the help of proton pumping b) It produces a high energy molecule by releasing a free CoA-SH (and therefore breaking a high energy thioester bond) c) It produces a high energy molecule with the help of decarboxylation d) None of the above are true e) It produces a high energy molecule with the help of oxidationarrow_forwardWhat is the first step in glycogen degradation? a) remodeling of the glycogen substrate b) activation of the T state of phosphorylase b c) release of glucose 1-phosphate from glycogen d) formation of glucose 6-phosphate from glucose 1-phosphate e) isomerization of glucose 1-phosphate to glucose 6-phosphatearrow_forward3-day -old female newborn with a deficiency of mitochondrial carbamoyl phosphate synthetase develops seizures and lapses into a coma. Which of the following changes in blood concentration is the most likely cause?A) Decreased glucoseB) Increased ammoniaC) Increased ketone bodiesD) Increased lactateE) Increased ureaarrow_forward
- Listed are some hypothetical medical conditions, describe their effect on cellular respiration (specifically refer to the effect they will have on energy production). a) A person is unable to take glucose into their cells. b) A mutation occurs in the ATP synthase protein and it is inactive. c) The mitochondrial inner membrane is very permeable to H+.arrow_forwardIf PFK is activated in the liver, which of the following statements would be false? a) There are high levels of fructose 2,6 bisphosphate b) PFK is in the R-state c) Glycolysis would be activated d) AMP levels are low e) Gluconeogenesis is inhibited in the liverarrow_forwardGlycogenolysis requires which of the following combination of enzymes? A) Glycogen synthase and branching enzyme. OB) Glycogen synthase, x-1,6-glucosidase, and debranching enzyme. OC) Glycogen phosphorylase, x-1,6-glucosidase, and branching enzyme. OD) Glycogen phosphorylase, x-1,6-glucosidase, and debranching enzyme.arrow_forward
- Which of the following condenses with oxaloacetate to form citrate? A) carboxybiotin B) cis-aconitate C) acetyl-CoA D) oxalosuccinate E) succinyl-phosphatearrow_forwardIsozymes: d) One way of regulating metabolic pathways is through isozymes. What is an isozyme? e) Provide a concrete example of an isozyme from carbohydrate metabolism. f) From your chosen isozyme in part b), describe how it is regulated differently in various cells.arrow_forwardWhich of the following statements is INCORRECT? OA) The inhibition of phosphofructokinase leads to the inhibition of hexokinase. B) Fructose-1,6-bisphosphate activates pyruvate kinase. OC) In the liver, phosphofructokinase is activated by citrate. OD) GLUT5 transports fructose.arrow_forward
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