The Krebs cycle reaction shown below is catalyzed by __ enzyme and ___ pays for this reaction note only major metabolites are shown    a. Synthetase, hydrolysis of acetyl CoA b. Synthase, hydrolysis of acetyl CoA c. Synthase, hydrolysis of NADH d. Synthetase, hydrolysis of ATP

I've stated that acetyl-CoA is perhaps the most central compound to our metabolic processes. Explain why I would make such a bold statement in the context of the metabolic processes we've covered so far.

For each step of the citric acid cycle, name the enzyme responsible for the chemical transformation that occurs and classify the enzyme type: Step 1. Step 2. Step 3. Step 4. Step 5. Step 6. Step 7. Step 8. i. oxidoreductase (oxidases, reductases, dehydrogenases) ii. transferase (transaminases, kinses) iii. hydrolase (lipases, proteases, nucleases, carbohydrases, phosphateses) iv. lyase (dehydratase, decarboxylase, deaminase, hydratase) v. isomerase (racemases, mutases) vi. ligase (synthetases, carboxylaces) Enzyme Name Enzyme Type

Which of the following molecules shown are the reduced products produced in the citric acid cycle whose reduction directly helped drive oxidation? Select all that apply. Ensure you are selecting the product forms of the molecule, which here means the reduced form, and are only considering redox reactions! Do not include the pyruvate processing steps -- just the citric acid cycle itself. A. GDP B. NADH C. FAD D. Acetyl-CoA E. NAD+ F. CoA G. FADH2 H. GTP I. QH2 J. Q

You are a genetic analyst and you have a patient with inherited defects of glycolysis. Specifically, this patient has severe symptoms that stem from issues in their erythrocytes (red blood cells). You find that your patient has a deficiency in Hexokinase (HK). Given this information and keeping in mind what you learned about the steps of glycolysis, bisphosphoglycerate (BPG), and the importance of 2,3 BPG for hemoglobin oxygen binding what do you predict will be the effect of this mutation? Select all that apply. decreased 2,3BPG concentrations reduced flow of metabolites through glycolysis increased 2,3BPG concentrations increased flow of metabolites through glycolysis decreased hemoglobin oxygen affinity increased hemoglobin oxygen affinity 000000

The structure of a metalloenzyme active site is down below(black picture). Describe, from a chemical and structural perspective, how the reactive site is designed to facilitate its catalytic reaction. The example below suggests the level of detail that is required. Make sure that you explain what the metal is doing, what the reaction is, and its biological significance.

7) The following questions apply to glycolysis (figure 3-41 on page 79 of the 12th edition), the Krebs cycle (figure 3-44 on page 82) and to oxidative phosphorylation (figure 3-45 on page 84). Calculate the total amount of ATP produced from one glucose molecule if: a. The oxidation of NADH + H* to NAD* + 2H* produced 4 ATP. b. The oxidation of FADH₂ to FAD + 2H* produced 1 ATP. c. Each step of the Krebs cycle that produces NADH+H* produced FADH2 instead. d. Each step of the Krebs cycle that produces FADH2 produced NADH + H+ instead. e. Sucrose is substituted for glucose.

Can you please help me answer the following questions. An enzymatic pathway is organized so that the final product will act as a competitive inhibitor to the first enzyme in the pathway. This is an example of: A. denaturation of a substrate enzyme complex B. positive feedback inhibition C. negative feedback inhibition D. competive binding of a product

GAP + Pi + NAD+ ⟹1,3-BPG + NADH (Reaction 1)      1,3-BPG + ADP  ⟹ 3-PG + ATP (Reaction 2) Which of the following statements concerning the information above is true? Select all that apply. A.Reaction 2 is an example of substrate level phosphorylation B.These reactions are written in a direction that would indicate gluconeogenesis is occurring in the liver C.The linking of Reaction 1 and Reaction 2 by the intermediate 1,3-BPG is an example of coupling of reactions D.Reaction 1 shows a redox reaction where the carbon skeleton is oxidized to generate electrons for a soluble electron carrier E.These reactions are irreversible under cellular conditions

The following reaction, the last reaction in beta-oxidation, is an example of a: Enzyme Enzyme-H S-CoA S-COA H2C H3C CoA s–CoA C H2 CH2 R S-COA S-COA S-COA O A. Nucleophilic acyl substitution O B. Electrophilic addition OC. Nucleophilic addition D. Aldol condensation O E. Hydrohalogenation