Biochemistry
9th Edition
ISBN: 9781319114671
Author: Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher: W. H. Freeman
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If 14CO2 (radioactive carbon) were incorporated into the TCA cycle via the Pyruvate Carboxylase reaction which of the following molecules would contain radioactive carbon?
a. Oxaloacetate
b. Citric Acid
c. Isocitrate
d. Alpha-ketoglutarate
e. Succinyl-CoA
f .Succinate
g. Fumarate
h. Malate
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- Gluconeogensis uses nearly all of the same enzymes as those in ____, and is a(an) ______ reaction. Select one: a. Citric Acid Cycle anabolic b. citric acid cycle, catabolic c. glycolysis, anabolic d. glycolysis, catabolic e. none of the abovearrow_forwardIn the reaction catalyzed by malate dehydrogenase, which of the following molecules is classified as the reduced donor? a. Malate b. Oxaloacetate c. Fumerate d. FAD e. FADH2 f. NAD+ g. NADHarrow_forwardBefore a fatty acid can undergo β-oxidation, it must be activated and then shuttled across the inner mitochondrial membrane. The activating agent and shuttle molecule are, respectively: A. CoA and carnitine B. CoA and citrate C. acetyl CoA and carnitine D. acetyl CoA and citratearrow_forward
- 1. Which of the following TCA cycle intermediates is also a metabolite in gluconeogenesis? a. Oxaloacetate b. Pyruvate c. Citrate d. Succinate e. Succinyl CoAarrow_forwardWhich of the following enzymes do not catalyze a reaction in the citrate cycle that produces CO2 as a product? Choose one or more: OA. isocitrate dehydrogenase OB. fumarase L C. succinate dehydrogenase O D. succinyl-CoA synthetasearrow_forwardGlyceraldehyde 3-phosphate dehydrogenase is used to do which of the following steps of glycolysis Select one: a. 1,3 Bisphosphoglycerate is converted to 3-phosphoglycerate b. Phosphoenolpyruvate is converted to pyruvate c. 2-phosphoglycerate is converted to Phosphoenolpyruvate d. Glyceraldehyde-3-phosphate is converted to 1,3 Bisphosphoglycerate e. Fructose-6-phosphate is converted to Fructose-1,6,bisphosphate f. Dihydroxyacetone (Glycerone Phosphate) is converted to Glyceraldehyde-3-phosphate g. Fructose-1,6 Bisphosphate is converted to Dihydroxyacetone and Glyceraldehyde-3-phosphate h. Glucose-6-phosphate is converted to Fructose-6-phosphate i. 3-phosphoglycerate is converted 2-phosphoglycerate j. Glucose is converted to Glucose-6-phosphatearrow_forward
- Which of the following enzymes possesses a catalytic mechanism extremely similar to that of the Pyruvate Dehydrogenase Complex? A. the isocitrate dehydrogenase B. the succinate dehydrogenase C. the alpha-ketoglutarate dehydrogenase D. the malate dehydrogenasearrow_forwardAll of the following classes of enzymes catalyze the Fatty acid synthesis except a. synthetase b. Synthase c. Carboxylase d. Dehydrgenarrow_forwardIn TCA cycle, FADH2 is formed in reaction(s) catalyzed by O a. Succinyl-CoA synthetase O b. Succinate dehydrogenase O c. Aconitase O d. Isocitrate dehydrogenase Oe. Citrate synthasearrow_forward
- In Yeast, pyruvate can be directly converted into: A. acetyl-CoA and ethanol B. acetyl-CoA only C. lactate only D. ethanol onlyarrow_forwardAre the following up or down regulation of phosphorylation? (Note: It assumes that the enzymes were involved in glycoysis) a. Phosphofructokinase-2 b. Pyruvate Kinase c. Phosphofructokinase-1 d. Pyruvate Dehydrogenase Kinasearrow_forwardWhen acetyl-CoA containing radioactively labeled carbon atoms is fed to cells, the CO, produced is not initially radioactive. However, molecules of citrate and oxaloacetate are radioactive. Only after some time has passed will radioactive CO2 be released. What is the best explanation for this observation?arrow_forward
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