The insertion of transposable elements into genes can alter the normal pattern of expression. In the following situations, describe the possible consequences on gene expression.a. A LINE inserts into an enhancer of a human gene. b. A transposable element contains a binding site for a transcriptional repressor and inserts adjacent to a promoter. c. An Alu element inserts into the 3′ splice (AG) site of an intron in a human gene. d. A Ds element that was inserted into the exon of a maize gene excises imperfectly and leaves three base pairs behind in the exon. e. Another excision by that same Ds element leaves two base pairs behind in the exon. f. A Ds element that was inserted into the middle of an intron excises imperfectly and leaves five base pairs behind in the intron.
Gene Interactions
When the expression of a single trait is influenced by two or more different non-allelic genes, it is termed as genetic interaction. According to Mendel's law of inheritance, each gene functions in its own way and does not depend on the function of another gene, i.e., a single gene controls each of seven characteristics considered, but the complex contribution of many different genes determine many traits of an organism.
Gene Expression
Gene expression is a process by which the instructions present in deoxyribonucleic acid (DNA) are converted into useful molecules such as proteins, and functional messenger ribonucleic (mRNA) molecules in the case of non-protein-coding genes.
The insertion of transposable elements into genes can
alter the normal pattern of expression. In the following
situations, describe the possible consequences on gene
expression.a. A LINE inserts into an enhancer of a human gene.
b. A transposable element contains a binding site for a
transcriptional repressor and inserts adjacent to a
promoter.
c. An Alu element inserts into the 3′ splice (AG) site of
an intron in a human gene.
d. A Ds element that was inserted into the exon of a
maize gene excises imperfectly and leaves three base
pairs behind in the exon.
e. Another excision by that same Ds element leaves
two base pairs behind in the exon.
f. A Ds element that was inserted into the middle of
an intron excises imperfectly and leaves five base pairs
behind in the intron.
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