Prolactin is a protein hormone that, among other things, enables mammals to produced milk. Prolactin is secreted from cells in the pituitary gland in response to eating, mating, ovulation, and nursing. a. Prolactin is encoded by the PRL A segment of the PRL gene and its regulatory regions are shown below. The +1 site (*) and part of the promoter (#) of PRL are indicated. What is the PRL mRNA transcribed from the PRL gene? 5'-AAGCCGACCGGATATACGACGCCATGAACATGACAGGATCGCCATGG-3' 3'-TTCGGCTGGCCTATATGCTGCGGTACTTGTACTGTCCTAGCGGTACC-5' b. What is the 5'-UTR of PRL? Lleing the mRNA you transcrib what are the first 9 mino aci rolactin that are translated?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
icon
Related questions
Question
Prolactin is a protein hormone that, among other things, enables mammals to produced milk. Prolactin is secreted from cells in the pituitary gland in response to eating, mating, ovulation,
and nursing.
a. Prolactin is encoded by the PRL A segment of the PRL gene and its regulatory regions are shown below. The +1 site (*) and part of the promoter (#) of PRL are indicated. What is the PRL
mRNA transcribed from the PRL gene?
5'-AAGCCGACCGGATATACGACGCCATGAACATGACAGGATCGCCATGG-3'
3'-TTCGGCTGGCCTATATGCTGCGGTACTTGTACTGTCCTAGCGGTACC-5'
#### *
b. What is the 5'-UTR of PRL?
c. Using the mRNA you transcribed in part a, what are the first 8 amino acids of prolactin that are translated?
cis face
trans face
MTOC
Rough ER
Golgi
complex
Cell membrane
c. In what organelle is prolactin glycosylated? What motor protein would be used to transport prolactin from the rough ER to this organelle?
d. Where does exocytosis occur? What motor protein would be used to transport prolactin from the site of its glycosylation to the site of its exocytosis?
e. If this cell was stained with an antibody specific for y (gamma) tubulin, where would we expect to see the cell stained in this immunohistochemistry experiment?
Transcribed Image Text:Prolactin is a protein hormone that, among other things, enables mammals to produced milk. Prolactin is secreted from cells in the pituitary gland in response to eating, mating, ovulation, and nursing. a. Prolactin is encoded by the PRL A segment of the PRL gene and its regulatory regions are shown below. The +1 site (*) and part of the promoter (#) of PRL are indicated. What is the PRL mRNA transcribed from the PRL gene? 5'-AAGCCGACCGGATATACGACGCCATGAACATGACAGGATCGCCATGG-3' 3'-TTCGGCTGGCCTATATGCTGCGGTACTTGTACTGTCCTAGCGGTACC-5' #### * b. What is the 5'-UTR of PRL? c. Using the mRNA you transcribed in part a, what are the first 8 amino acids of prolactin that are translated? cis face trans face MTOC Rough ER Golgi complex Cell membrane c. In what organelle is prolactin glycosylated? What motor protein would be used to transport prolactin from the rough ER to this organelle? d. Where does exocytosis occur? What motor protein would be used to transport prolactin from the site of its glycosylation to the site of its exocytosis? e. If this cell was stained with an antibody specific for y (gamma) tubulin, where would we expect to see the cell stained in this immunohistochemistry experiment?
Expert Solution
trending now

Trending now

This is a popular solution!

steps

Step by step

Solved in 5 steps

Blurred answer
Knowledge Booster
Genomic studies
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, biology and related others by exploring similar questions and additional content below.
Similar questions
Recommended textbooks for you
Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
Biology
ISBN:
9780134580999
Author:
Elaine N. Marieb, Katja N. Hoehn
Publisher:
PEARSON
Biology 2e
Biology 2e
Biology
ISBN:
9781947172517
Author:
Matthew Douglas, Jung Choi, Mary Ann Clark
Publisher:
OpenStax
Anatomy & Physiology
Anatomy & Physiology
Biology
ISBN:
9781259398629
Author:
McKinley, Michael P., O'loughlin, Valerie Dean, Bidle, Theresa Stouter
Publisher:
Mcgraw Hill Education,
Molecular Biology of the Cell (Sixth Edition)
Molecular Biology of the Cell (Sixth Edition)
Biology
ISBN:
9780815344322
Author:
Bruce Alberts, Alexander D. Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Publisher:
W. W. Norton & Company
Laboratory Manual For Human Anatomy & Physiology
Laboratory Manual For Human Anatomy & Physiology
Biology
ISBN:
9781260159363
Author:
Martin, Terry R., Prentice-craver, Cynthia
Publisher:
McGraw-Hill Publishing Co.
Inquiry Into Life (16th Edition)
Inquiry Into Life (16th Edition)
Biology
ISBN:
9781260231700
Author:
Sylvia S. Mader, Michael Windelspecht
Publisher:
McGraw Hill Education