Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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The following are DNA fragments containing a small gene.  The top strand is the coding strand. Transcribe all  groups and translate.

FIND THE POSSIBLE MUTATIONS 

 

 

Group B - MUTATION

5’-GGCAATGGGTTTGTGAAATTCTAAAAGTTTTTAATTC-3’

3’-CCGTTACCCAAACACTTTAAGATTTTCAAAAATTAAG-5’

 

Group C-

5’-GGCAATGGGTTTGTGCAATTCTAAGAGTTTTTAATTC-3’

3’-CCGTTACCCAAACACGTTAAGATTCTCAAAAATTAAG-5’

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Step 1- Introduction

The genetic information of all living organisms (except some viruses) is stored in the cell in the form of DNA. This stored information is converted into the protein, via two main steps, 1. Transcription and 2. Translation.
In the transcription, the information present in the DNA is copied in the form of mRNA. Transcription takes place in the nucleus of the cell (In eukaryotes). In translation, the copied information in the form of mRNA is used to make proteins. 
The triplet codon (genetic code) is the group of three consecutive nucleotides that code for a specific amino acid. Such amino acids come together to form the polypeptide chain that folds into the unique confirmation and act as protein. 
There are 61 different types of codons that code for 20 amino acids and three stop codons that terminate the peptide chain formation. The one amino acid can be coded by more than one codon, this phenomenon is called redundancy of genetic codon. 
The mutation is the change in the nucleotide sequence of DNA. The mutation can take place due to some replication error or due to environmental factors such as UV exposure or chemical exposure. The main three types of mutations that can be seen in the DNA sequence are 1. Base substitution mutation (Point mutation, silence mutation, missense mutation, and nonsense mutation) 2.  Deletion, 3. Insertion.

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