Tamoxifen needs an enzyme that is not found in the genes of Asians, but is used to prevent breast cancer in Asian women and to treat breast cancer in Asian women and men, how is that? Is it useful? Explain with pictures please
Q: "Using the concepts and techniques you have learned from the two labster simulations, provide…
A: Monogenic inherited disorders are brought about by a mutation in one single gene. Every one of these…
Q: Genetic instability in the form of point mutations, chromosome rearrangements, and epigenetic…
A: Answer: Introduction: Mutation- These are the random heritable changes that occurs in the DNA…
Q: The BRCA genes produce DNA repair proteins. Genetic testing is available that can determine if a…
A: BRCA1 (BReast CAncer gene 1) and BRCA2 (BReast CAncer gene 2) are proteins that aid in the repair of…
Q: Explain how methylation of cytosine nucleotides can affect gene expression in one way. Explain how…
A: DNA is a polymer made up of a nucleotide monomer. The double strands of the DNA are joined through a…
Q: Having a mutant form of the gene XYZ is associated with a higher incidence of cancer than is seen in…
A: A mutant gene XYZ is linked with higher incidences of causing cancer than other mutation. The XYZ…
Q: researchers identified the important role of GNAQ in both development and cancer
A: GNAQ is G Protein subunit Alpha Q.It is a protein coded gene present on chromosome 9.It is a guanine…
Q: Mutations in three broad classes of genes have been implicated in the onset of cancer. Can you…
A: A Mutation occurs when a DNA gene is damaged or changed in such a way as to alter the genetic…
Q: What are the biggest challenges that mutations pose to oncologists and cancer biologists who seek to…
A: Mutations are one of the biggest challenges to the Oncologists and cancer biologists who wish and…
Q: Why are people more likely to develop cancer as they age? Why does inheriting a mutation increase…
A: Cancer is the name given to a collection of related diseases.In all types of cancer,some of the…
Q: Which of the following mutations is MOST likely to cause cancer? A) a mutation that causes a cyclin…
A: Introduction- Cancer is a caused by the disturbances in the controls which regulate cells and this…
Q: You found a protein called X in colon cancer patients that is over-expressed and is associated with…
A: Metastasis is the process by which cancer cells spread from the primary tumor site to other parts of…
Q: what category of cancer-related genes is it possible to find inherited variants that are associated…
A: Answer is option 3.
Q: Recently, a type of genetically modified fish has been approved for sale for human consumption. The…
A: genetically modified organisms are much more capable to enhance the production rate in a short time.…
Q: Insulin-like growth factor 2 (IGF2) is located on chromosome 11. My maternal copy of chromosome 11…
A: The IGF2 gene provides instructions for making a protein called insulin-like growth factor 2. It…
Q: Although tobacco smoking is responsible for a large number of human cancers, not all smokers develop…
A: Cancer refers to the uncontrolled cell division caused by the mutations in the genes which control…
Q: In order for a new variant to become dominant in the population, it must have a(n) _________________…
A: Not all varieties have an impact on evolution. Hereditary variations found in egg or sperm cells are…
Q: Discuss how oncogenes and tumor suppressor genes are related to genes involved in the control of…
A: Tumor suppressor genes are the regular genes present in the genome which are important for the…
Q: What 2 things are most responsible for controlling gene expression
A: Gene encodes protein in our body. It inherits from parents to offsprings. Study of all Genes in our…
Q: 3. Figure on the right shows a DNA microarray assay of gene expression levels. In this microarray if…
A: Micro arrays are utilised for the determination of gene expression patterns in specific tissues or…
Q: All cells of the body, with a few exceptions, contain the same genome. What is the name of the…
A: Cells is the structural and functional unit of life. The cell is made up of several organelles and…
Q: Cancer is caused by many different types of gene mutations. Some mutations are in proto-oncogenes,…
A: Cells split into new cells so that the body uses them and cancer starts with this wonderful…
Q: Which of the following statements describing mutations causing cancer is false? Group of answer…
A: Mutation refers to any change in base sequence of DNA. Mutagen is physical or chemical agent that…
Q: Suppose Nicole recently learned that she inherited a mutant BRCA1 allele from her mother, who had…
A: BRCA1 is a tumor suppressor gene usually expressed in breast cells. It is responsible for repairing…
Q: Write TRUE or FALSE. If false, write the word/s that make(s) the statement incorrect. 1.Metabolic…
A: Since you have asked multiple questions, we will slove the first question for you. If you want any…
Q: Mutations in proto-oncogenes that turn them into oncogenes tend to be dominant, while cancer-causing…
A: Tumor suppressor genes are the genes that suppress the formation of tumors in the cells or tissues…
Q: Your friend sends you two cancerous cell lines to examine and determine possible mutations. The…
A: Here we know about cancer development due to mutation.
Q: Many human cancers result when a normal gene mutates and leads to uncontrolled growth (a tumor).…
A: Introduction Cancer is a popular disease now a day. In the US, 1 in 2 women and 1 in 3 men develop…
Q: You have a patient slated to undergo somatic cell gene therapy to alleviate a cystic fibrosis…
A: Answer: Cystic fibrosis is the result of homozygous recessive mutations in the CFTR gene.
Q: Imagine you are working in a lab that is developing a novelty rose that smells like a stinkhorn…
A: Introduction :- Recombination DNA technology is used for making clones of genes ( gene cloning) ,…
Q: relationship that may exist between mutations and cancer
A: Any permanent change occurring in the DNA base sequence is referred to as a mutation. The mutation…
Q: Many of the mutations in cancer samples are not necessarily driver mutations, but rather passenger…
A: Hematologic childhood cancer can develop in any part of the body, including the blood and lymph…
Q: Do more mutations necessarily mean that more cancer-causing genes are faulty? Why or why not?
A: Biotechnology is a wide range of studies where it uses its techniques with biological systems to…
Q: You are studying cancer progression in mice. Your results show the following pathway in which two…
A: Nature of given proteins in cell division and cancer.
Q: Give a possible explanation for why a mutation in a single gene does not always lead to cancer.
A: Mutation in a gene is defined as any change or alteration in the structure, and hence, function of…
Q: Drivers are mutations that drive the cancer process; passengers are mutations that arise randomly in…
A: Cancer is the uncontrolled division or growth of the cells. The causes of cancer differ widely but…
Q: Which of the following statements about cancer is correct? A. Cancer stem cells can make tumors…
A: Cancer is a disease that occurs when the cells in the body start dividing abnormally. They go out of…
Q: How gene therapy or cell therapy can help cure diseases? What kinds of diseases do gene and cell…
A: Since you have posted a question with multiple sub-parts, we will solve the first three subparts for…
Q: Several research studies are under way that involve the use of genetherapies to inhibit the growth…
A: Rribonucleic acid (RNA) is genetic material which is made up of nucleotides, which consist of a…
Q: Sequencing the human genome, the development of microarray technology, and personal genomics promise…
A: To describe: How are Sequencing the human genome, the development of microarray technology, and…
Q: Tumor suppressor genes and oncogenes are implicated in carcinogenesis. However, one can predict…
A: Oncogene is a gene that is responsible for the formation of cancer cells in the body. Mostly the…
Q: Mutations in the BRCA genes have been shown to be related to a higher incidence of breast cancer in…
A: BRCA is a gene that produces proteins that help repair damaged DNA. everyone has two copies of the…
Q: Cancer-causing mutations in genes can have different effects on the protein products expressed.
A: An Oncogene is a gene that encodes a protein that has the potential to transform cells in culture or…
Q: What common mutation occurs in many human cancers? Explain how it can have this effect.
A: Cancers are originated from genetic mutations. Genetic mutations are of two types; acquired and…
Q: One major goal of modern cancer therapy is toidentify small molecules—anticancer drugs—that canbe…
A: Anticancer drugs are used against cancer. Chemotherapy drugs kill cancer cells by stopping them from…
Q: Imagine you have used cBioportal and breast cancer patient datasets and identified a…
A: Introduction :- Cancer is defined as the uncontrolled and un-regulated proliferation of cells , due…
Q: what are the rolls that the p53 gene and RAS protein take on when trying to stop a cancer cell from…
A: Given: Role of p53 and RAS protein to stop a cancer cell from replication. What happens if mutation…
Tamoxifen needs an enzyme that is not found in the genes of Asians, but is used to prevent breast cancer in Asian women and to treat breast cancer in Asian women and men, how is that? Is it useful? Explain with pictures please
Step by step
Solved in 2 steps
- How would a human cell normally change its expression of the gene for tyrosine aminotransferase? adipose cells will turn on this gene in the presence of glucocorticoids liver cells will turn on this gene in the presence of glucocorticoids liver cells will turn on this gene in the absence of glucocorticoids liver cells will turn off this gene in the presence of glucocorticoids adipose cells will turn off this gene in the absence of glucocorticoidsa. When gene probes, fi ngerprinting, and sequencing make it possible for you to know about genetic diseases in you or one of your children, would you wish to use this technology to fi nd out? b. What if it were used as a screen for employment or insurance? c. Most of us would agree to growth hormone therapy for a child with dwarfi sm, but how do we deal with parents who want to give growth hormones to their 8-year-old son so that he will be “better at sports”?A patient comes into your clinic exhibiting generic cancer symptoms. In order to help form a diagnosis, you ask about patient history and they tell you that they worked for years in an agricultural job, primarily in handling food for large bovine animals and then later working with insect pesticide treatment of grain fields. You decide to test for elevated levels of the environmental agent(s) in their body and focus your cancer diagnosis on based on the established associations of epigentic effects and cancer. O nickel and cadmium; stomach and skin cancer O benzene; breast, prostate and thyroid cancer O polycyclic aromatic hydrocarbons and benzene; lung, breast, stomach and skin cancer O arsenic and endocrine disruptors; skin, bladder, liver and kidney cancer
- Why are leptin injections less helpful for most overweight people than for mice with a mutation in the leptin gene?Tumor suppressor genes and oncogenes are implicated in carcinogenesis. However, one can predict whether a gene potentially encodes for a protein that influences carcinogenesis by examining their mutational profile. You sequence the genome of 4 cancers and identify 3 genes of interest. Which of the following genes has the best potential to an oncogene? Tumor 1 Tumor 2 Tumor 3 Tumor 4 Gene A S24F, N465T R33T T345S, G366R P367E, P368Y Gene B S34R, F360I S34R V254I S34E, T67Y Gene C S24F, I322E C255I, E344D S34E, P367E* Google Translate x + re.com/courses/49703/quizzes/244266/take/questions/5315835 Understanding BAC-23 better might be the difference in curing cancer and saving millions of lives! You must sequence its genome and find the genetic code that makes the cancer curing protein. After running several tests, you have found the correct gene segment to be: GGG UCG ACA CUC UUU. Remember that bacteria are weird and their genes are made from a single strand with ribose sugar backbones! 1. Give the correct DNA template for this bacterial gene segment (GGG UCG ACA CUC UUU). ***Please use the following format or it will be marked incorrect*** Example: ABC DEF GHI JKL MNO, all caps, organized in threes with a space in between. Please make my life easier 2. Using the genetic code provided (GGG UCG ACA CUC UUU), translate this gene segment. ***Please use the following format or it will be marked incorrect*** Example: ABC DEF GHI JKL MNO, all caps, organized in threes with a space in between. Please make…
- 7) The protein VEGF plays an important role in stimulating the formation of new blood vessels. In some circumstances, cancer cells will produce too much VEGF. The drug PTC299 is currently being researched as a potential anti-cancer drug. It works by binding to VEGF mRNA, stopping this mRNA from being read by the ribosome. Therefore, not as much VEGF protein is produced. (National Cancer Institute. nd. NCI Drug Dictionary. Retrieved from: https://www.cancer.gov/publications/dictionaries/cancer-drug/def/vegf-inhibitor-ptc299) a) If approved, what kind of cancer treatment would it be considered (radiotherapy, gene therapy. anti-angiogenesis)? b) Briefly explain why you think PTC299 fits the kind of cancer treatment you indicated in a). Use information from the text to support your answer. c) Would PTC299 be considered a traditional or a targeted therapy?WHAT ELSE CAN I ADD TO THIS DISCUSSION In general, what is gene regulationand what are the consequences if this process goes awry? Gene regulation is the process used to control the timing, location and amount of genes expressed. The process is carried out by a variety of mechanisms, including regulatory proteins and chemical modification of DNA. It’s key to the ability of an organism to respond to environmental changes. If the gene regulation process goes awry, these alterations are called mutations and can accumulate over a lifetime. Errors in genes that control cell division can cause cancer and other genetic mutations to take place.This is a blank question. Thank you in advance, Bloom Syndrome Bloom syndrome is a rare genetic disorder. It is characterized by short stature and a long narrow face with prominent nose and ears. There is also increased sensitivity to light. People who have the disorder often develop rashes on their face, forearms, and hands when they have been exposed to the sun. In addition, these people often suffer from chronic obstructive pulmonary disorder (COPD) and have a higher chance of developing cancer. The cause of this genetic disorder is a mutation in the BLM gene located on chromosome 15. The immediate effect of this mutation is that there is a defect in the functioning of the DNA helicase enzyme. What would be the effect of this mutation on DNA replication? What stage of the cell cycle would be most affected?
- Mutations in the BRCA genes have been shown to be related to a higher incidence of breast cancer in humans, and genetic tests are available that enable women to discover whether they carry versions of the gene associated with high risk. However, even early detection of breast cancer does not guarantee a cure. What considerations can you think of for and against advising women to take the tests? ·On the image, you can see the results of a DNA microarray used for cancer prognosis, where tissue samples from healthy and cancerous tissues were analyzed. cDNA from healthy cells and cancer cells were labeled with green and red fluorescence, respectively, mixed equally, and hybridized with the chip. It is known that gene A is more highly expressed in breast cancer type I, while genes B and C have lower expression in type II, which is highly aggressive. Based on the gene expression levels shown in the image, the cancer sample does not correspond to either type I or type II breast cancer, why is that?How gene therapy or cell therapy can help cure diseases? What kinds of diseases do gene and cell therapy treat? What is the difference between gene therapy and cell therapy? What are the different approaches to gene and cell therapy? What risks are associated with gene and cell therapy? What are the ethical issues associated with gene and cell therapy? What are stem cells? Why are stem cells so important in gene and cell therapy?