с TTC TTTA TTG CTT CTC A H G T CTA CTG Phe Leu Leu с TCT TCC TCA TCG CCT ccc CCA Ser val ATA ACA ATG Net ACG GTT GCT GTC GCC GTA GTG Pro CCG ATT ACT ATC Ile ACC Thr TAT TAC GCA GCG A TAA TAG CAT CAC CAA Ala ) Mutant E makes Met-His-Val-Arg CAG AAT AAC Tyr His ) Mutant D makes Met-His-Val-Gly-Asn-Thr AAA Lys AAG GAT Asp GAC GAA Glu GAG Standard genetic code Gln TGT TGC TGA TGG Trp CGT CGC CGA CGG AGT AGC Asn GICACIGTAIGGT|AAC|ACTIGAGICCC|TGACC-3' CICTG|CATICCG|TTG|TGA|CTC|GGG|ACTGG-5' et His Val Gly Asn Thr Glu Pro STOP G Cys Arg FURGTURO HUKO HLAG AGA AGG GGT GGC GGA GGG Ser DNA segment below encodes the short peptide of 8 amino acids. Mutant strains produce Itered proteins shown below. g the genetic code table provided, a) describe the exact single base pair alteration that have occurred in the DNA to give rise to each mutant protein, b) name the kind of mutatio and c) show how it leads to the mutant protein. me all mutations in each strain are due to a single event involving one nucleotide. **in the table indicates a Stop codon] Arg Gly

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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T
с
A
G
T
TCT
TCC
TCA
TCG
CCT
ccc
CTA
CCA
CTG
CCG
ATT
ACT
ATC Ile ACC Thr
TTC
TTA
TTG
CTT
CTC
Phe
Leu
Leu
ATA
ATG Net
GTT
GTC
GTA
GTG
с
Val
Ser
Pro
ACA
ACG
GCT
GCC
GCA
GCG
TAT
TAC
TAA
TAG
CAT
CAC
CAA
CAG
AAT
AAC
AAA
AAG
A
Ala
Tyr
✰✰✰
2) Mutant E makes Met-His-Val-Arg
His
1) Mutant D makes Met-His-Val-Gly-Asn-Thr
G
Cys
TGA
TGG Trp
CGT
CGC
TGT
TGC
Gln
GAT
Asp
GAC
GAA
Glu
GAG
Standard genetic code
Asn
5'-ATGICACIGTAIGGT|AAC|ACTIGAGICCC|TGACC-3'
3'-TAC|CTG|CATICCG|TTG|TGA|CTC|GGG|ACTGG-5'
Met His Val Gly Asn Thr Glu Pro STOP
Lys
CGA
CGG
AGT
AGC
AGA
AGG
GGT
GGC
GGA
GGG
Arg
FURG TUAO HUKO HLAG
Ser
The DNA segment below encodes the short peptide of 8 amino acids. Mutant strains produce
the altered proteins shown below.
Arg
Using the genetic code table provided, a) describe the exact single base pair alteration that
must have occurred in the DNA to give rise to each mutant protein, b) name the kind of mutation
it is, and c) show how it leads to the mutant protein.
Assume all mutations in each strain are due to a single event involving one nucleotide.
[note: ** in the table indicates a Stop codon]
Gly
Transcribed Image Text:T с A G T TCT TCC TCA TCG CCT ccc CTA CCA CTG CCG ATT ACT ATC Ile ACC Thr TTC TTA TTG CTT CTC Phe Leu Leu ATA ATG Net GTT GTC GTA GTG с Val Ser Pro ACA ACG GCT GCC GCA GCG TAT TAC TAA TAG CAT CAC CAA CAG AAT AAC AAA AAG A Ala Tyr ✰✰✰ 2) Mutant E makes Met-His-Val-Arg His 1) Mutant D makes Met-His-Val-Gly-Asn-Thr G Cys TGA TGG Trp CGT CGC TGT TGC Gln GAT Asp GAC GAA Glu GAG Standard genetic code Asn 5'-ATGICACIGTAIGGT|AAC|ACTIGAGICCC|TGACC-3' 3'-TAC|CTG|CATICCG|TTG|TGA|CTC|GGG|ACTGG-5' Met His Val Gly Asn Thr Glu Pro STOP Lys CGA CGG AGT AGC AGA AGG GGT GGC GGA GGG Arg FURG TUAO HUKO HLAG Ser The DNA segment below encodes the short peptide of 8 amino acids. Mutant strains produce the altered proteins shown below. Arg Using the genetic code table provided, a) describe the exact single base pair alteration that must have occurred in the DNA to give rise to each mutant protein, b) name the kind of mutation it is, and c) show how it leads to the mutant protein. Assume all mutations in each strain are due to a single event involving one nucleotide. [note: ** in the table indicates a Stop codon] Gly
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