Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN: 9780134580999
Author: Elaine N. Marieb, Katja N. Hoehn
Publisher: PEARSON
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- Part A You were sequencing a region of 200 kb in Effrenium voratum (a member of the family Symbiodiniaceae) and you found two genes, an insulator, and two enhancers, as shown below. Gene A Promoter gene A Enhancer I Enhancer I| Insulator Promoter gene b Gene B Q: What would happen if you do some gene editing and you move the insulator between both enhancers? The newly positioned insulator allows enhancer II to activate gene B transcription The newly positioned insulator allows enhancer I to hyperactivate gene B transcription The new positioning of the insulator prevents gene A expression It will be unaltered The newly positioned insulator prevents enhancer II from stimulating the transcription of gene Barrow_forwardIf the operator gene is a non-transcribable region of DNA, and the promoter is upstream of the operator, what does this mean for the operator gene during transcription? Does it get removed before? Or is it always an intron that gets spliced out?arrow_forwardA newly identified protein from the cells of the Panopyra plant on Pandora was shown to inhibit translation of its target genes by binding to the 5’ UTR of the mRNA and preventing ribosome binding. A possible way this inhibition may be relieved by an sRNA would be: Group of answer choices a)The sRNA acts as a silencer, suppressing the inhibitory protein and allowing translation to take place. b)The sRNA acts as a decoy, sequestering the inhibitory protein and allowing translation to take place. c)The sRNA acts as a marker, flagging the inhibitory protein for ubiquitination and allowing translation to take place.arrow_forward
- a. How do bacteria increase the efficiency of gene expression? Is this possible in eukaryotes? b. A mutation in the promoter of Gene K disrupts an enzyme binding site and results in the loss of Gene K expression. Is this change in gene expression likely happening at the transcriptional or the translational level? Explain. c. Propose three different mutations to prevent initiation, elongation, and termination of bacterial transcription, respectively. Explain how/why each mutation would prevent its respective step. (Hint: mutations can be in genes that encode proteins or regulatory DNA sequences)arrow_forwardWhich of the following statements is false? a mutation in a 5' or 3' splice site must alter the sequence of the protein encoded by a gene a missense mutations replaces one amino acid with a different amino acid a mutation in a promoter is unlikely to alter the sequence of the polypeptide encoded by a gene a mutation in a transcriptional terminator is unlikely to alter the sequence of a protein encoded by a gene. a frameshift mutation changes the sequence of a protein 0000arrow_forwardUsing the transcription unit diagrammed below, in which exons are represented by blue boxes and introns are represented by the connecting lines. You discover a single base deletion in region E of this DNA sequence. Regarding transcription, this mutation will likely: 1.) Result in an alteration to the mRNA sequence. 2.)Have no effect on transcription or the mRNA sequence 3.)Prevent transcription at the TATAA box 4.) Result in an increase or decrease in the amount of mRNA transcribedarrow_forward
- Suppose you had isolated a new transcription factor and wanted to know which genes this protein might regulate. Is there any way that you could use a cDNA microarray of the type shown in the picture to approach this question?arrow_forwardBONUS One benefit of operons in bacteria is that they AYO allow for the bacteria to utilize a wide variety of carbon sources. B) O allow for coordinated gene expression of related genes on one mRNA controlled by one promoter. C) O do not need ligands and regulatory proteins as single genes would. D) O do not need any modification of the proteins after they are expressed.arrow_forwardExpression of a gene, in terms of greater production of the protein it encodes, could be increased by ... Question 12 options: A) increasing transcription of that gene. B) inhibiting proteases that break down the protein it encodes C) increasing the half life of its mRNA transcript D) A and C E) A, B and Carrow_forward
- There may be more than one answer for each Expression of mRNA can be regulated by which of the following? a.) RNA interference b.) presence of vectors c.) antisense RNA d.) blocking of poly(A)polymerase Which of the following occur during processing of pre-mRNA? a.) removal of exons b.) removal of noncoding sequences c.) addition of 5’ cap structure d.) addition of poly-A tailarrow_forwardyou design an ideal promoter for a gene to be highly expressed in E. coli cells? Describe strategies and explainarrow_forward
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