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Q: In drosophila, a recessive mutation (m-) of a maternal effect gene results in an abnormal phenotype…
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Polarity of oocyte of Drosophila
What is the difference between the anterior and posterior determinant for the oocyte?
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- Polarity of oocyte of DrosophilaWhat are the cells surrounding the oocyte? Are they germ-line or somatic in origin?“In the early Drosophila embryo, the establishment of different body regionor tissues along, on the one hand, the anteroposterior axis and, on theother, the dorsoventral axis are initiated by clues provided by the egg’smother; however the nature of those signals and the way in which theyoperate is completely different”. Discuss whether this statement is correct.Recalling the eye pigment pathway in Drosophila, identify the phenotypes of the flies with the following genotypes. (w=white, bw=brown, cn=cinnabar red, st=scarlet red, se=sepia brown)
- A Drosophila embryo dies during early embryogenesis due to arecessive allele of a maternal effect gene called bicoid. The wildtypeallele is designated bicoid +. What are the genotypes and phenotypesof the embryo’s mother and maternal grandparents?Which Position-effect variegation in Drosophila?8.18 Irradiatioh of Drosophila sperm produces transloca- tions between the X chromosome and autosomes, between the Y chromosome and autosomes, and between different autosomes. Translotations between the X and Y chromosomes are not produced. Explain the absence of X-Y translocations. The birth of this child prompted the Dentons' physician to order a chromosome study of parents and child. The results of the study are shown in the accompanying fig- ure. Chromosome banding was done, and all chromo- somes were normal in these individuals, except some copies of number 6 and number 12. The number-6 and number-12 chromosomes of mother, father, and child are shown in the figure (the number 6 chromosomes are the larger pair): Child Mrs. Denton Mr. Denton a. Does either parent have an abnormal karyotype? If so, which parent has it, and what is the nature of the abnormality? b. How did the child's karyotype arise? (What pairing and segregation events took place in the parents?) e. Why is the child…
- The Wnt planar polarity signaling pathway nor-mally ensures that each wing cell in Drosophila has a sin-gle hair. Overexpression of the Frizzled gene from a heat-shock promoter (hs-Fz) causes multiple hairs to grow frommany cells (Figure Q15–5A). This phenotype is suppressedif hs-Fz is combined with a heterozygous deletion (DshΔ)of the Dishevelled gene (Figure Q15–5B). Do these resultsallow you to order the action of Frizzled and Dishevelledin the signaling pathway? If so, what is the order? Explainyour reasoningWhat is the signaling pathway that mediates the organizing activity of the A/P organizer in the Drosophila wing disc? Describe two experiments that suggest this pathway functions to organize pattern and promote growth along the anterior/posterior axis of wing imaginal discs.A Drosophila male is heterozygous for a reciprocaltranslocation between an autosome and the Y chromosome. The part of the autosome now present onthe Y chromosome contains the dominant mutationLyra (shortened wings); the other (normal) copyof the same autosome is Lyra+. This male is nowmated with a true-breeding, wild-type female. Whatkinds of progeny would be obtained, and in whatproportions?
- EXTRANUCLEAR INHERITANCE In drosophila, a recessive mutation (m-) of a maternal effect gene (MEG) results in an abnormal phenotype wherein homozygous (m-m-) females produce eggs that cannot support embryonic development. Homozygous (m-m-) males, however, can still produce viable sperm. Using m+ to denote a normal gene, determine the genotypes and phenotypes of the F1s produced by a cross between a heterozygous female and a recessive male. From the offspring, backcross the recessive female with the paternal strain. What are the genotypes and phenotypes of the F2s? with COMPLETE cross for both cases.Describe the molecular process of X-chromosome inactivation.This description should include the three phases of inactivationand the role of the Xic. Explain what happens to the X chromosomes during embryogenesis, in adult somatic cells, and duringoogenesis.he Drosophila oocyte/embryos A-F show the expression patterns of various mRNAs. Which is the distribution of the hairy mRNA? A B C D E F
