Phospholipase A2 causes the release of what fatty acid from membrane phospholipids? What chemical class of messengers is produced from this fatty acid?
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Phospholipase A2 causes the release of what fatty acid from membrane phospholipids? What chemical class of messengers is produced from this fatty acid?
Phospholipase is an enzyme that breaks down phospholipids into fatty acids and other lipophilic compounds. Acids cause bound calcium to be released from cellular storage, resulting in an increase in free cytosolic Ca2+, an important step in calcium signaling that controls intracellular functions. The sort of reaction that they catalyze distinguishes them into four major classes: A, B, C, and D.
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- How does the chemical nature of lipid-soluble messengers relate to the general principle of physiology that physiological processes are dictated by the laws of chemistry and physics?Define Phospholipase C : IP3-DAG pathway,with diagram?The general principle of physiology that structure is a determinant of—and has coevolved with—function can be considered at the molecular, cellular, and organ levels. How is this principle illustrated by the binding of messengers to their receptors?
- What are the characteristics of receptors binding to messengers?As an intracellular messenger molecule, explain the role of Ca2+ ion? (( cell signaling book , metabolism book )Another general principle of physiology states that physiological processes require the transfer and balance of matter and energy. How is energy balance-related to intracellular signaling?
- What do Lipid-soluble messengers include?Distinguish among the four types of extracellular chemical messengers with regard to their source and the distance to their target cells.Second-messenger systems ultimately bring about the desired cell response by inducing a change in the shape and function of particular designated intracellular proteins. (True or false?)
- The class of enzyme that acts as an effector molecule to generate two lipid messengers from PIP2 is a ___________; the lipid messenger products include the membrane-bound lipid _______ and the soluble lipid messenger ________. Phospholipase; diacylglycerol (DAG); inositol 1,4,5-trisphosphate (IP3) Phospholipid kinase; diacylglycerol (DAG); inositol 1,4,5-trisphosphate (IP3) Phospholipid phosphatase; inositol 1,4,5-trisphosphate (IP3); diacylglycerol (DAG) Phospholipid kinase; inositol 1,4,5-trisphosphate (IP3); diacylglycerol (DAG)Please Name and explain the four classes of chemical messengers.What term is used to indicate signaling chemicals that bind to membrane receptors? Which type of membrane receptor is most important in directing intracellular events by promoting formation of second messengers?