Enumerate and describe the classes of enantiomeric drug Discuss briefly the different methods of enantioanalysis. Give the advantage of using potentiometry over chromatography
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- Enumerate and describe the classes of enantiomeric drug
- Discuss briefly the different methods of enantioanalysis.
- Give the advantage of using potentiometry over chromatography
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- Briefly explain this statement "Preformulation studies help to find the drug performance and the development of a dosage form"-explain this with different drug properties and example? Please answer at your own easy words.Enumerate and describe at least three (3) big scale pharmaceutical methods on reducing particle size.Discuss the principles and applications of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry in molecular diagnostics.
- How can you use Uv-visible spectroscopy in qualitative and quantitive analysis of drugs? Please answer shorty at your own words. Answer should be to the point(specific 4-5 lines)What is the minimal resolution required for gleaning insights into structures of drug-drug target complex? 100A 2.5A 5A 10A 0.5AIdentify the objectives and methodology of the article below: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824784/ Riboswitches as Drug Targets for Antibiotics Vipul Panchal* and Ruth Brenk*
- Construct a schematic diagram on how ACE inhibition assay is performed based on the protocol given. Explain how the colorimetric method measures ACE inhibitory activity. Protoc reference:TRUE OR FALSE Properties of a drug suitable for transdermal use include: High molecular mass Low lipophilicity Low required daily dose Low potency High partition coefficient Problems with opioid TDDS include: Poor patient compliance Allergy Constipation Respiratory depression Cognitive dysfunctiona) Explain the general advantages in the use of radiopharmaceuticals for treatment as opposed to irradiation using external sources of radiation. b) Relate these advantages to explain why radiopharmaceuticals are often used in the treatment of i) prostate cancer (brachytherapy) ii) thyroid cancer (iodine-131 treatment)
- a) Explain the general advantages in the use of radiopharmaceuticals for treatment as opposed to irradiation using external sources of radiation. b) Relate these advantages to explain why radiopharmaceuticals are often used in the treatment of i) prostate cancer(brachytherapy) ii) thyroid cancer (iodine-131 treatment)what is pharmacophore? what is the importance of pharmacophore in drug discovery?What is the definition of a crude drug? Describe the drug's origins.