peptide C=O bond. O The imidazole group acts as a general base and extracts a proton from serine activating it to attack the substrate O The imidazole group acts as a general base and extracts a proton from aspartate activating it to attack the substrate O The imidazole group acts as a general base and extracts a proton from aspartate allowing it to activate serine by transferring a protor

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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What is the function of Histidine as part of the catalytic triad?
O The alcohol group of histidine makes a nucleophilic attack on a
peptide C=O bond.
O The imidazole group acts as a general base and extracts a proton
from serine activating it to attack the substrate
O The imidazole group acts as a general base and extracts a proton
from aspartate activating it to attack the substrate
O The imidazole group acts as a general base and extracts a proton
from aspartate allowing it to activate serine by transferring a proton
Transcribed Image Text:What is the function of Histidine as part of the catalytic triad? O The alcohol group of histidine makes a nucleophilic attack on a peptide C=O bond. O The imidazole group acts as a general base and extracts a proton from serine activating it to attack the substrate O The imidazole group acts as a general base and extracts a proton from aspartate activating it to attack the substrate O The imidazole group acts as a general base and extracts a proton from aspartate allowing it to activate serine by transferring a proton
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