People are unable to break down trimethyl-amine, a compound in the diet, resulting in a fish-like odor in sweat, urine and breath. 1. Name the trait that causes these symptoms. 2. If this is a heritable trait, what is the mode of inheritance? 3. What is the type of mutation cause this syndrome, explain the change

Fragile X syndrome why is interesting Fragile X syndrome  What are the symptoms or characteristics of this disorder or trait?  What is the prevalence of the trait or disorder? What are the main genetic factors? s the genetic cause of this disorder or trait known? What gene(s) have been proven to be involved? Or, if not known, what genes are thought to be involved? Is it caused by a single gene? polygenic? Multifactorial? Devote a few paragraphs to this   This could be one of the longest parts of the paper, if you choose to focus on this. If multiple genes are thought to be involved, discuss the specific role of at least one of them in depth  (if known). Is the gene you’re discussing thought to play a major or a minor role in the phenotype? What chromosome is it on? What protein does it code for, and how might the protein possibly contribute to the phenotype? If no genes have yet been identified, indicate this, and devote at least one paragraph to any current efforts to determine which…

1. Give the genetic cause (chromosomal abnormality and genes affected), and major characteristics of the syndrome Miller Dieker syndrome Wolf-Hirschhorn syndrome Chronic myeloid leukemia/Philadelphia chromosome Acute promyelocytic leukemia Cri-du-chat

Due to a nucleotide substitution, the fourth residue of H3 in a specific tissue cell of an organism is no longer lysine. 1. Would this have an impact on Bromodomains or Chromodomains? 2. How would this affect gene expression of that region of the gene in the cell?

a. Each person inherits one copy of the Huntington's Disease gene from each parent. Explain why the negative control sample (from an unaffected individual) only produced one band.   b. Explain why the positive control sample (from an individual affected by Huntington’s disease) produced twobands.

8. Dioxin (in the human diet!) and ethidium bromide (used in labs to see DNA using UV light) are classified as because they insert themselves in between adjacent DNA bases. 9. UV light can cause two adjacent pyrimidines to form a (Fig 18.21). 10. Study Figure 18.26. What is the difference between black, green and red grapes relative to expression of genes that produce anthocyanin pigments? Possible answers: retrotransposon prevents pigment expression; partial removal of retrotransposon allows partial pigment expression; absence of retrotransposon allows normal pigment expression. a. Black: b. Green : C. Red:

1.  What is the pattern of inheritance of 5-Alpha Reductase 2 Deficiency? answer choices: X-linked recessive X-linked dominant autosomal recessive autosomal dominant maternal/mitochondrial Y-linked 2.  What is the likely genotype of individual V-8?    a = recessive allele A = dominant allele   What is the likely genotype of individual V-8?    a = recessive allele A = dominant allele answer choices: XaY XAY aa Aa AA 3.  Imagine that individual V-8 marries a female cousin who is a carrier of the 5αRD mutation. What is the probability that they will have a child who has the disorder?   Enter your answer as a fraction

Inheritance of the diseases by the II-3 male from his father rules out what type of inheritance explain your reasoning

20. The pedigree to the right shows the results of SSR genotyping of a family. The grandmother is affected with a fully penetrant, adult onset autosomal disease. The exact genetic lesion is not known, but it has been 22 mapped to be 4 centimorgans from the genotyping SSR. What is the likelihood that Child B will suffer from the disease? 13 12 32 a. 2% b. 4% C. 48% d. 50% 12 32 A B

One of the first drugs used for targeted cancer therapy is tamoxifen, used to treat estrogen-receptor breast cancer. What general conclusions can you draw about the targeted drug therapy and genotype?