One concern about using genetically-modified organisms is that many of the methods used to create them introduce into the genome DNA from a different species (i.e. foreign DNA). Which of the following methods has the lowest potential of introducing foreign DNA into the genome? A. A gene knockout in mouse using homologous recombination in ES cells B. Introduction of a P element vector into the Drosophila germ-line C. Deletion mutations introduced by CRISPR/Cas9 D. Microinjection of a transgene into a mouse pronucleus

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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One concern about using genetically-modified organisms is that many of the methods used to create them introduce into the genome DNA from a different species (i.e. foreign DNA). Which of the following methods has the lowest potential of introducing foreign DNA into the genome?

A. A gene knockout in mouse using homologous recombination in ES cells
B. Introduction of a P element vector into the Drosophila germ-line
C. Deletion mutations introduced by CRISPR/Cas9
D. Microinjection of a transgene into a mouse pronucleus

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