Offspring Parents Normal CFNS Family number Father Mother Male Female Male Female normal CFNS normal CFNS 5 2 normal CFNS normal CFNS CFNS normal 2 8. 10a 3 2 normal CFNS CFNS normal 10b 2 12 13a normal CFNS 2 13b CFNS normal 0. 2 7b CFNS normal 2 O NO1010

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Craniofrontonasal syndrome (CFNS) is a birth defect in which
premature fusion of the cranial sutures leads to abnormal head shape, widely spaced eyes, nasal clefts, and various other skeletal abnormalities. George Feldman and his colleagues looked at several families in which offspring had CFNS and recorded the results shown in the following table (G. J. Feldman. 1997. Human Molecular Genetics 6:1937–1941).

Q. On the basis of these results, what is the most likely mode of inheritance for CFNS? 

Offspring
Parents
Normal
CFNS
Family number
Father Mother Male Female Male Female
normal CFNS
normal CFNS
5
2
normal CFNS
normal CFNS
CFNS normal
2
8.
10a
3
2
normal CFNS
CFNS normal
10b
2
12
13a
normal CFNS
2
13b
CFNS normal
0.
2
7b
CFNS normal
2
O NO1010
Transcribed Image Text:Offspring Parents Normal CFNS Family number Father Mother Male Female Male Female normal CFNS normal CFNS 5 2 normal CFNS normal CFNS CFNS normal 2 8. 10a 3 2 normal CFNS CFNS normal 10b 2 12 13a normal CFNS 2 13b CFNS normal 0. 2 7b CFNS normal 2 O NO1010
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